Abstract “In silico organisms” are computational genome-scale metabolic models used in
systems and synthetic biology developed by constraint-based metabolic simulations using …

The current upper thermal limit for life as we know it is approximately 120° C.
Microorganisms that grow optimally at temperatures of 75° C and above are usually referred …

Introduction Protein thermostability is an important field for its evolutionary perspective of
mesophilic versus thermophilic relationship and for its industrial/therapeutic applications …

Background The ambient temperature of all habitats is a key physical property that shapes
the biology of microbes inhabiting them. The optimal growth temperature (OGT) of a …

Metabolic modelling approaches have become the powerful tools in modern biology. These
mathematical models are widely used to predict metabolic phenotypes of the organisms or …

Antibiotic‐associated infections with Clostridioides difficile are a severe and often lethal risk
for hospitalized patients, and can also affect populations without these classical risk factors …

We evolved Thermus thermophilus to efficiently co-utilize glucose and xylose, the two most
abundant sugars in lignocellulosic biomass, at high temperatures without carbon catabolite …

Rice straw is a major crop residue which is burnt in many countries, creating significant air
pollution. Thus, alternative routes for disposal of rice straw are needed. Biotechnological …

Metabolic processes are altered in cancer cells, which obtain advantages from this
metabolic reprogramming in terms of energy production and synthesis of biomolecules that …

The increase in greenhouse gases with high global warming potential such as methane is a
matter of concern and requires multifaceted efforts to reduce its emission and increase its …