Palladium-catalyzed aerobic oxidation reactions have been the focus of industrial
application and extensive research efforts for nearly 60 years. A significant transition …

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

Selective aerobic oxidation of organic molecules is a fundamental and practical challenge in
modern chemistry. Effective solutions to this problem must overcome the intrinsic reactivity …

The transformation of unsaturated hydrocarbons through the action of metal complexes
continues to constitute a very important field of organometallic chemistry, particularly when …

A catalyst for the intramolecular direct arylation of a broad range of simple and heterocyclic
arenes with aryl iodides, bromides, and chlorides has been developed. These reactions …

Through the introduction of an aryl chloride substituent, the selectivity of palladium-catalyzed
direct arylation may be diverted to provide alternative regioisomeric products in high yields …

A novel method for the synthesis of oxindoles is described. In the presence of catalytic
palladium acetate and 2-(di-tert-butylphosphino) biphenyl, α-chloroacetanilides are …

Because of the presence of their π-system, electron-rich alkenes and alkynes are prone to
react as nucleophiles with various electrophiles. The complexation of an alkene or alkyne …

Significant progress has been made in the direct arylation of simple arenes. A number of
catalyst systems have been developed which enable the intramolecular direct arylation of …

Die selektive aerobe Oxidation organischer Verbindungen ist eines der fundamentalsten
Probleme der modernen organischen Chemie. Effektive Lösungen müssen die spezifische …