Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

Potential anticancer properties and mechanisms of action of formononetin

D Jiang, A Rasul, R Batool, I Sarfraz… - BioMed research …, 2019 - Wiley Online Library
Nature, a vast reservoir of pharmacologically active molecules, has been most promising
source of drug leads for the cure of various pathological conditions. Formononetin is one of …

Eupatilin: a natural pharmacologically active flavone compound with its wide range applications

B Nageen, I Sarfraz, A Rasul, G Hussain… - Journal of Asian …, 2020 - Taylor & Francis
Abstract Eupatilin (5, 7-dihydroxy-3′, 4′, 6-trimethoxyflavone) is a pharmacologically
active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known …

Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone

A Rasul, M Khan, M Ali, J Li, X Li - The Scientific World Journal, 2013 - Wiley Online Library
Alantolactone and isoalantolactone, main bioactive compounds that are present in many
medicinal plants such as Inula helenium, L. Inula japonica, Aucklandia lappa, Inula …

Fraxinus: A Plant with Versatile Pharmacological and Biological Activities

I Sarfraz, A Rasul, F Jabeen, T Younis… - Evidence‐Based …, 2017 - Wiley Online Library
Fraxinus, a member of the Oleaceae family, commonly known as ash tree is found in
northeast Asia, north America, east and western France, China, northern areas of Pakistan …

Crosstalk between Phosphoinositide 3‐kinase/Akt signaling pathway with DNA damage response and oxidative stress in cancer

A Karimian, SM Mir, H Parsian… - Journal of cellular …, 2019 - Wiley Online Library
Abstract The phosphatidylinositol 3‐kinases (PI3K)/Akt signaling pathway is one of the well‐
characterized and most important signaling pathways activated in response to DNA …

Maltol improves APAP-induced hepatotoxicity by inhibiting oxidative stress and inflammation response via NF-κB and PI3K/Akt signal pathways

Z Wang, W Hao, J Hu, X Mi, Y Han, S Ren, S Jiang… - Antioxidants, 2019 - mdpi.com
Maltol, a food-flavoring agent and Maillard reaction product formed during the processing of
red ginseng (Panax ginseng, CA Meyer), has been confirmed to exert a hepatoprotective …

Cytotoxic effects of mono-and di-rhamnolipids from Pseudomonas aeruginosa MR01 on MCF-7 human breast cancer cells

K Rahimi, TB Lotfabad, F Jabeen, SM Ganji - Colloids and Surfaces B …, 2019 - Elsevier
Rhamnolipids produced by P. aeruginosa MR01 were fractionated into mono-and di-
rhamnolipids, and their dominant congeners, Rha-C 10-C 10 and Rha-Rha-C 10-C 10, were …

Induction of apoptosis by costunolide in bladder cancer cells is mediated through ROS generation and mitochondrial dysfunction

A Rasul, R Bao, M Malhi, B Zhao, I Tsuji, J Li, X Li - Molecules, 2013 - mdpi.com
Despite the availability of several therapeutic options, a safer and more effective modality is
urgently needed for treatment of bladder cancer. Costunolide, a member of sesquiterpene …

[HTML][HTML] Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota

Y Zhao, X Liu, C Ding, Y Zheng, H Zhu, Z Cheng… - Journal of …, 2022 - Elsevier
The purpose of this experiment was to investigate the anti-hepatic fibrosis effect of Aronia
melanocarpa polysaccharide (AMP) on TAA-induced liver fibrosis mice and its mechanism …