Two observations stimulated the interest in vitamin B-6 and alkaline phosphatase in brain:
the marked increase in plasma pyridoxal phosphate and the occurrence of pyridoxine …

Abstract The Senescence-Accelerated Mouse (SAM) represents a group of inbred mouse
strains developed as a model for the study of human aging and age-related diseases …

The axon is a long projection connecting a neuron to its targets. Here, the axons of cultured
rat cortical neurons were isolated with micropatterned chips that enable the separation of …

Nasu-Hakola disease (NHD) is a recessively inherited rare disorder characterized by a
combination of neuropsychiatric and bone symptoms which, while being unique to this …

Background It is difficult to study the mechanisms of the metabolic syndrome in humans due
to the heterogeneous genetic background and lifestyle. The present study investigated …

目的: 探讨淫羊藿苷(ICA) 对快速老化小鼠SAMP10 脑组织单胺类及氨基酸类神经递质的影响.
方法: 本实验采取8 月龄快速老化小鼠SAMP10 为实验对象, 随机分为模型SAMP10 组 …

Proteomics is one of the commonly used techniques to explore the protein composition or
protein modification status in various healthy or diseased brain tissues in the past decades …

AIM: To investigate the effects of icariin (ICA) on monoamine and amino acid
neurotransmitters in senescence accelerated mouse prone/10 (SAMP10). METHODS: The 8 …

Brain senescence is as obvious as death. It is associated with structural as well as functional
compromises of the brain. Decline in cognitive function can also be associated with aging …