A growing literature suggests that exposure to adverse social conditions may accelerate
biological aging, offering one mechanism through which adversity may increase risk for age …

This manuscript reviews recent evidence supporting the utility of telomeres and
mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse …

Early adversity, in the form of abuse, neglect, socioeconomic status and other adverse
experiences, is associated with poor physical and mental health outcomes. To understand …

Telomeres play an important part in aging and show relationships to lifetime adversity,
particularly childhood adversity. Meta-analyses demonstrate reliable associations between …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Early life adversity (ELA) is associated with a higher risk for diseases in adulthood. Although
the pathophysiological effects of ELA are varied, there may be a unifying role for the immune …

Telomeres are specialised structures at the end of linear chromosomes. They consist of
tandem repeats of the hexanucleotide sequence TTAGGG, as well as a protein complex …

Telomeres are a repeated sequence-of bases found at the ends of chromosomes. In
humans, this sequence is TTAGGG, which is repeated over 2000 times. Telomeres protect …

A poor socioeconomic environment and social adversity are fundamental determinants of
human life span, well-being and health. Previous influenza pandemics showed that …

Background Stress exposure occurring across the lifespan increases risk for disease,
potentially involving telomere length shortening. Stress exposure during childhood and …