Neuroprotection in stroke: the importance of collaboration and reproducibility

AA Neuhaus, Y Couch, G Hadley, AM Buchan - Brain, 2017 - academic.oup.com
Acute ischaemic stroke accounts for 6.5 million deaths per year, and by 2030 will result in
the annual loss of over 200 million disability-adjusted life years globally. There have been …

Reactive astrogliosis in stroke: Contributions of astrocytes to recovery of neurological function

NR Sims, WP Yew - Neurochemistry international, 2017 - Elsevier
Alterations in neuronal connectivity, particularly in the “peri-infarct” tissue adjacent to the
region of ischemic damage, are important contributors to the spontaneous recovery of …

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

M Goyal, BK Menon, WH Van Zwam, DWJ Dippel… - The Lancet, 2016 - thelancet.com
Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Full-waveform inversion imaging of the human brain

L Guasch, O Calderón Agudo, MX Tang, P Nachev… - NPJ digital …, 2020 - nature.com
Magnetic resonance imaging and X-ray computed tomography provide the two principal
methods available for imaging the brain at high spatial resolution, but these methods are not …

e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients

S Nagel, D Sinha, D Day, W Reith… - … Journal of Stroke, 2017 - journals.sagepub.com
Background The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is
an established 10-point quantitative topographic computed tomography scan score to …

[HTML][HTML] A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial.

P Langhorne, O Wu, H Rodgers, A Ashburn… - Health Technology …, 2017 - europepmc.org
A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised
controlled trial. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …

Quantitative lesion water uptake in acute stroke computed tomography is a predictor of malignant infarction

G Broocks, F Flottmann, A Scheibel, A Aigner, TD Faizy… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Early selection of patients with acute middle cerebral artery
infarction at risk for malignant edema is critical to initiate timely decompressive surgery. Net …

Outcomes of endovascular thrombectomy in the elderly: a 'real-world'multicenter study

A Alawieh, RM Starke, AR Chatterjee, A Turk… - Journal of …, 2019 - jnis.bmj.com
Background The efficacy of endovascular thrombectomy (ET) for acute ischemic stroke (AIS)
in octogenarians is still controversial. Objective To evaluate, using a large multicenter cohort …

Mechanical thrombectomy in acute ischemic stroke: a systematic review

A Lambrinos, AK Schaink, I Dhalla, T Krings… - Canadian Journal of …, 2016 - cambridge.org
Although intravenous thrombolysis increases the probability of a good functional outcome in
carefully selected patients with acute ischemic stroke, a substantial proportion of patients …

Therapeutic management of ischemic stroke

P Bindal, V Kumar, L Kapil, C Singh, A Singh - … Archives of Pharmacology, 2024 - Springer
Stroke is the third leading cause of years lost due to disability and the second-largest cause
of mortality worldwide. Most occurrences of stroke are brought on by the sudden occlusion of …