Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

The structure and function of the Na, K-ATPase isoforms in health and disease

MV Clausen, F Hilbers, H Poulsen - Frontiers in physiology, 2017 - frontiersin.org
The sodium and potassium gradients across the plasma membrane are used by animal cells
for numerous processes, and the range of demands requires that the responsible ion pump …

The unrecognized prevalence of primary aldosteronism: a cross-sectional study

JM Brown, M Siddiqui, DA Calhoun… - Annals of Internal …, 2020 - acpjournals.org
Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …

International histopathology consensus for unilateral primary aldosteronism

TA Williams, CE Gomez-Sanchez… - The Journal of …, 2021 - academic.oup.com
Objective Develop a consensus for the nomenclature and definition of adrenal
histopathologic features in unilateral primary aldosteronism (PA). Context Unilateral PA is …

Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Diagnosis and treatment of primary aldosteronism: practical clinical perspectives

WF Young Jr - Journal of internal medicine, 2019 - Wiley Online Library
Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment

A Vaidya, P Mulatero, R Baudrand… - Endocrine …, 2018 - academic.oup.com
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Hormones and aging: an endocrine society scientific statement

AR Cappola, RJ Auchus… - The Journal of …, 2023 - academic.oup.com
Multiple changes occur across various endocrine systems as an individual ages. The
understanding of the factors that cause age-related changes and how they should be …

Role of the renin-angiotensin-aldosterone system beyond blood pressure regulation: molecular and cellular mechanisms involved in end-organ damage during …

N Muñoz-Durango, CA Fuentes, AE Castillo… - International journal of …, 2016 - mdpi.com
Arterial hypertension is a common condition worldwide and an important predictor of several
complicated diseases. Arterial hypertension can be triggered by many factors, including …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …