A review of the combination of experimental measurements and fibril‐reinforced modeling for investigation of articular cartilage and chondrocyte response to loading

P Julkunen, W Wilson, H Isaksson… - … methods in medicine, 2013 - Wiley Online Library
The function of articular cartilage depends on its structure and composition, sensitively
impaired in disease (eg osteoarthritis, OA). Responses of chondrocytes to tissue loading are …

Internal load-sharing in the human passive lumbar spine: Review of in vitro and finite element model studies

F Ghezelbash, H Schmidt, A Shirazi-Adl… - Journal of …, 2020 - Elsevier
Human lumbar motion segment is composed of various components with distinct
contributions to its gross mechanical response. By employing experimental and …

On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disk …

A Malandrino, JM Pozo, I Castro-Mateos… - … in Bioengineering and …, 2015 - frontiersin.org
Capturing patient-or condition-specific intervertebral disk (IVD) properties in finite element
models is outmost important in order to explore how biomechanical and biophysical …

A database of lumbar spinal mechanical behavior for validation of spinal analytical models

IAF Stokes, M Gardner-Morse - Journal of biomechanics, 2016 - Elsevier
Data from two experimental studies with eight specimens each of spinal motion segments
and/or intervertebral discs are presented in a form that can be used for comparison with …

Nonlinear stress-dependent recovery behavior of the intervertebral disc

SE Bezci, S Lim, GD O'Connell - Journal of the Mechanical Behavior of …, 2020 - Elsevier
The intervertebral disc exhibits complex mechanics due to its heterogeneous structure,
inherent viscoelasticity, and interstitial fluid-matrix interactions. Sufficient fluid flow into the …

Biomechanical response of intact, degenerated and repaired intervertebral discs under impact loading–Ex-vivo and In-Silico investigation

M Nikkhoo, JL Wang, M Parnianpour, M El-Rich… - Journal of …, 2018 - Elsevier
Understanding the effect of impact loading on the mechanical response of the intervertebral
disc (IVD) is valuable for investigating injury mechanisms and devising effective therapeutic …

Association between measures of vertebral endplate morphology and lumbar intervertebral disc degeneration

S Duran, M Cavusoglu, HG Hatipoglu… - Canadian …, 2017 - journals.sagepub.com
Purpose The aim of this study was to evaluate the association between vertebral endplate
morphology and the degree of lumbar intervertebral disc degeneration via magnetic …

Development of a Computational Model of the Mechanical Behavior of the L4–L5 Lumbar Spine: Application to Disc Degeneration

G Eremina, A Smolin, J Xie, V Syrkashev - Materials, 2022 - mdpi.com
Degenerative changes in the lumbar spine significantly reduce the quality of life of people. In
order to fully understand the biomechanics of the affected spine, it is crucial to consider the …

腰椎间盘结构, 盘内压力及不同载荷的影响: 生物力学研究进展

魏晓宁, 王艳, 裴飞 - 中国组织工程研究, 2015 - cjter.com
背景: 腰椎间盘突出是临床引起腰腿疼的最主要原因, 严重影响患者的日常生活, 学习与工作,
而对腰椎间盘的生物力学特点进行研究, 对预防和治疗腰椎间盘疾病具有重要指导意义. 目的 …

The intravertebral distribution of bone density: correspondence to intervertebral disc health and implications for vertebral strength

AI Hussein, TM Jackman, SR Morgan, GD Barest… - Osteoporosis …, 2013 - Springer
This study's goal was to determine associations among the intravertebral heterogeneity in
bone density, bone strength, and intervertebral disc (IVD) health. Results indicated that …