The role of the VEGF family in coronary heart disease

Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

The role of the VEGF family in atherosclerosis development and its potential as treatment targets

SA Dabravolski, VA Khotina, AV Omelchenko… - International journal of …, 2022 - mdpi.com
The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis,
lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of …

Disproportionate left atrial myopathy in heart failure with preserved ejection fraction among participants of the PROMIS-HFpEF study

RB Patel, CSP Lam, S Svedlund, A Saraste, C Hage… - Scientific reports, 2021 - nature.com
Impaired left atrial (LA) function in heart failure with preserved ejection fraction (HFpEF) is
associated with adverse outcomes. A subgroup of HFpEF may have LA myopathy out of …

Increased levels of circulating angiogenic cells and signaling proteins in older adults with cerebral small vessel disease

A Kapoor, A Gaubert, A Marshall, IB Meier… - Frontiers in Aging …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (SVD) is associated with increased risk of stroke
and dementia. Progressive damage to the cerebral microvasculature may also trigger …

Causal association of cytokines and growth factors with stroke and its subtypes: A Mendelian randomization study

G Chen, T Lin, M Wu, G Cai, C Wu, Q Ding, J Xu… - Molecular …, 2024 - Springer
Cytokines and growth factors contribute to nerve growth and angiogenesis and are
associated with the development of vascular disease. This Mendelian randomization (MR) …

Atrial fibrillation: the role of hypoxia-inducible factor-1-regulated cytokines

S Babapoor-Farrokhran, D Gill, J Alzubi… - Molecular and Cellular …, 2021 - Springer
Atrial fibrillation (AF) is a common arrhythmia that has major morbidity and mortality. Hypoxia
plays an important role in AF initiation and maintenance. Hypoxia-inducible factor (HIF), the …

Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease

P Davidsson, S Eketjäll, N Eriksson… - Cardiovascular …, 2023 - academic.oup.com
Aims The vascular endothelial growth factor (VEGF) family is involved in pathophysiological
mechanisms underlying cardiovascular (CV) diseases. The aim of this study was to …

Defining the inflammatory microenvironment in the human cochlea by perilymph analysis: toward liquid biopsy of the cochlea

A Warnecke, NK Prenzler, H Schmitt, K Daemen… - Frontiers in …, 2019 - frontiersin.org
The molecular pathomechanisms in the majority of patients suffering from acute or
progressive sensorineural hearing loss cannot be determined yet. The size and the complex …

Distinct characteristics of VEGF‐D and VEGF‐C to predict mortality in patients with suspected or known coronary artery disease

H Wada, M Suzuki, M Matsuda, Y Ajiro… - Journal of the …, 2020 - Am Heart Assoc
Background VEGF‐D (vascular endothelial growth factor D) and VEGF‐C are secreted
glycoproteins that can induce lymphangiogenesis and angiogenesis. They exhibit structural …

Exploring the causal association of rheumatoid arthritis with atrial fibrillation: a Mendelian randomization study

J Rong, X Chen, N Jin, J Hong - Clinical Rheumatology, 2024 - Springer
Background It has been proved that rheumatoid arthritis (RA) patients have high incidence
of atrial fibrillation (AF). Nevertheless, whether they have causal relevance is uncertain. This …