Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

[HTML][HTML] Pathobionts in inflammatory bowel disease: origins, underlying mechanisms, and implications for clinical care

A Gilliland, JJ Chan, TJ De Wolfe, H Yang, BA Vallance - Gastroenterology, 2024 - Elsevier
The gut microbiota plays a significant role in the pathogenesis of both forms of inflammatory
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …

A plant genetic network for preventing dysbiosis in the phyllosphere

T Chen, K Nomura, X Wang, R Sohrabi, J Xu, L Yao… - Nature, 2020 - nature.com
The aboveground parts of terrestrial plants, collectively called the phyllosphere, have a key
role in the global balance of atmospheric carbon dioxide and oxygen. The phyllosphere …

Ulcerative colitis (primer)

T Kobayashi, B Siegmund, C Le Berre… - Nature Reviews …, 2020 - search.proquest.com
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown aetiology
affecting the colon and rectum. Multiple factors, such as genetic background, environmental …

Nutrition, IBD and gut microbiota: a review

MC Mentella, F Scaldaferri, M Pizzoferrato… - Nutrients, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract, characterized by an inflammatory process that requires lifelong …

Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease

Y Cao, K Cheng, M Yang, Z Deng, Y Ma, X Yan… - Journal of …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a chronic nonspecific disease with
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …

Novel fecal biomarkers that precede clinical diagnosis of ulcerative colitis

HJ Galipeau, A Caminero, W Turpin, M Bermudez-Brito… - Gastroenterology, 2021 - Elsevier
Background & Aims Altered gut microbiota composition and function have been associated
with inflammatory bowel diseases, including ulcerative colitis (UC), but the causality and …

Gut microbiome composition is associated with future onset of Crohn's disease in healthy first-degree relatives

JAR Garay, W Turpin, SH Lee, MI Smith, A Goethel… - Gastroenterology, 2023 - Elsevier
Background & Aims The cause of Crohn's disease (CD) is unknown, but the current
hypothesis is that microbial or environmental factors induce gut inflammation in genetically …

IL-23 in inflammatory bowel diseases and colon cancer

MF Neurath - Cytokine & growth factor reviews, 2019 - Elsevier
Studies in recent years have identified a pivotal role of the cytokine IL-23 in the
pathogenesis of inflammatory bowel diseases (IBD: Crohn´ s disease, ulcerative colitis) and …

The “Gum–Gut” axis in inflammatory bowel diseases: a hypothesis-driven review of associations and advances

KM Byrd, AS Gulati - Frontiers in immunology, 2021 - frontiersin.org
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper
airways and gastrointestinal tract; however, its connection to the rest of the body has been …