Mechanisms involved in the neurotoxicity and abuse liability of nitrous oxide: a narrative review

TM Brunt, W van den Brink… - International journal of …, 2022 - mdpi.com
The recreational use of nitrous oxide (N2O) has increased over the years. At the same time,
more N2O intoxications are presented to hospitals. The incidental use of N2O is relatively …

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities

BZ Schmidt, M Lehmann, S Gutbier, E Nembo… - Archives of …, 2017 - Springer
Neurotoxicity and developmental neurotoxicity are important issues of chemical hazard
assessment. Since the interpretation of animal data and their extrapolation to man is …

Metal ions influx is a double edged sword for the pathogenesis of Alzheimer's disease

P Wang, ZY Wang - Ageing Research Reviews, 2017 - Elsevier
Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …

Defective quality control autophagy in Hyperhomocysteinemia promotes ER stress and consequent neuronal apoptosis through proteotoxicity

B Kaur, PK Sharma, B Chatterjee, B Bissa… - Cell Communication and …, 2023 - Springer
Homocysteine (Hcy), produced physiologically in all cells, is an intermediate metabolite of
methionine and cysteine metabolism. Hyperhomocysteinemia (HHcy) resulting from an in …

Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia

A Kalani, PK Kamat, P Chaturvedi, SC Tyagi, N Tyagi - Life sciences, 2014 - Elsevier
Aim Exosomes, the nano-units (< 200 nm), released from diverse cell types in the
extracellular body fluid, possess non-immunogenic property and ability to cross the blood …

Moringa oleifera alleviates homocysteine-induced Alzheimer's disease-like pathology and cognitive impairments

YAR Mahaman, F Huang, M Wu… - Journal of …, 2018 - content.iospress.com
Alzheimer's disease (AD) is multifactorial with unclear etiopathology. Due to the complexity
of AD, many attempted single therapy treatments, like Aß immunization, have generally …

Polylactic acid microplastics induce higher biotoxicity of decabromodiphenyl ethane on earthworms (Eisenia fetida) compared to polyethylene and polypropylene …

Y Han, M Fu, J Wu, S Zhou, Z Qiao, C Peng… - Science of The Total …, 2023 - Elsevier
Decabromodiphenyl ethane (DBDPE) and microplastics (MPs), such as fossil-based
polymers polyethylene (PE), polypropylene (PP), and bio-based plastics polylactic acid …

Glia signaling and brain microenvironment in migraine

H Amani, A Soltani Khaboushan, GM Terwindt… - Molecular …, 2023 - Springer
Migraine is a complicated neurological disorder affecting 6% of men and 18% of women
worldwide. Various mechanisms, including neuroinflammation, oxidative stress, altered …

Sodium arsenite-induced learning and memory impairment is associated with endoplasmic reticulum stress-mediated apoptosis in rat hippocampus

H Sun, Y Yang, H Shao, W Sun, M Gu… - Frontiers in Molecular …, 2017 - frontiersin.org
Chronic arsenic exposure has been associated to cognitive deficits. However, mechanisms
remain unknown. The present study investigated the neurotoxic effects of sodium arsenite in …

Involvement of TRPM2 in the neurobiology of experimental migraine: focus on oxidative stress and apoptosis

Y Yazğan, M Nazıroğlu - Molecular Neurobiology, 2021 - Springer
Excessive Ca2+ influx and mitochondrial oxidative stress (OS) of trigeminal ganglia (TG)
have essential roles in the etiology of migraine headache and aura. The stimulation of …