Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling

F Grün, B Blumberg - Endocrinology, 2006 - academic.oup.com
Over the last two decades, the incidence of obesity and associated metabolic syndrome
diseases has risen dramatically, becoming a global health crisis. Increased caloric intake …

Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review

B Antizar-Ladislao - Environment international, 2008 - Elsevier
Tributyltin (TBT) is a toxic chemical used for various industrial purposes such as slime
control in paper mills, disinfection of circulating industrial cooling waters, antifouling agents …

Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes

S Kirchner, T Kieu, C Chow, S Casey… - Molecular …, 2010 - academic.oup.com
The environmental obesogen hypothesis proposes that pre-and postnatal exposure to
environmental chemicals contributes to adipogenesis and the development of obesity …

Obesogens: an environmental link to obesity

W Holtcamp - 2012 - ehp.niehs.nih.gov
The role of environmental chemicals in obesity has garnered increased attention in
academic and policy spheres, and was recently acknowledged by the Presidential Task …

Obesogenic endocrine disrupting chemicals: identifying knowledge gaps

A Veiga-Lopez, Y Pu, J Gingrich… - Trends in Endocrinology & …, 2018 - cell.com
Endocrine disrupting chemicals (EDCs) are compounds that are part of everyday consumer
products and industrial manufacturing processes. EDCs can interfere with the endocrine …

History on organotin compounds, from snails to humans

ACA Sousa, MR Pastorinho, S Takahashi… - Environmental chemistry …, 2014 - Springer
Organotin compounds are industrial chemicals used as biocides, polyvinyl chloride
stabilizers and industrial catalysts for the manufacture of silicone and polyurethane foams …

Organotin compounds: toxicokinetic aspects

KE Appel - Drug metabolism reviews, 2004 - Taylor & Francis
Organotin compounds have a broad range of applications. While dialkyltin compounds are
used primarily as stabilizers for plastics, trisubstituted organotins are mainly used as …

Accumulation and trophic transfer of organotins in a marine food web from the Danish coastal waters

J Strand, JA Jacobsen - Science of the Total Environment, 2005 - Elsevier
The presence of organotin compounds, eg, tributyltin (TBT) and triphenyltin (TPhT) including
the di-and monosubstituted breakdown products, was studied in a representative marine …

Tributyltin causes obesity and hepatic steatosis in male mice

Z Zuo, S Chen, T Wu, J Zhang, Y Su… - Environmental …, 2011 - Wiley Online Library
Organotin compounds such as tributyltin (TBT) have been used worldwide in agriculture and
industry as biocides, heat stabilizers, and chemical catalysts. However, few studies …

Toxicity and the cardiovascular activity of organotin compounds: a review

M Nath - Applied Organometallic Chemistry, 2008 - Wiley Online Library
A comprehensive review on toxicity of organotin compounds including sources of their
intake and mode of action, and cardiovascular activity of organotin compounds is presented …