Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause for dementia. There are many hypotheses about AD, including abnormal …

Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …

Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …

The ability to detect and respond to novel events is crucial for survival in a rapidly changing
environment. Four decades of neuroscientific research has begun to delineate the neural …

Alzheimer's disease (AD) is the most common form of degenerative dementia and is
characterized by progressive impairment in cognitive function during mid-to late-adult life …

Life's Journey If life is indeed a journey, then poetry must be the map that reveals all its
topographic possibilities… while science is the compass that keeps us from getting lost.—RT …

The basal forebrain cholinergic neurons (BFCN) provide the primary source of cholinergic
innervation of the human cerebral cortex. They are involved in the cognitive processes of …

The common marmoset (Callithrix jacchus) is a small, nonendangered New World primate
that is native to Brazil and has been used extensively in biomedical research. Historically the …

Studies of the function of the basal forebrain have focused on cholinergic neurons that
project to cortical and limbic structures critical for various cognitive abilities. Recent …

Cortical map plasticity is believed to be a key substrate of perceptual and skill learning. In
the current study, we quantified changes in perceptual ability after pairing tones with …