Most of the global population is deficient in long-chain marine omega-3s. In particular,
docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and …

Introduction: Individuals with bipolar disorder (BD) have higher rates of unhealthy lifestyles
and risk for medical comorbidities Research currently suggests that dietary factors may play …

Objectives The therapeutic use of nutrient-based 'nutraceuticals' and plant-based
'phytoceuticals' for the treatment of mental disorders is common; however, despite recent …

Introduction Emerging evidence suggests central roles of miRNAs in the pathogenesis of
bipolar disorder (BD). Exosomes are membrane-bound vesicles acting as “biological cargo …

Omega-3 fatty acids may be protective against bipolar disorder (BD), whereas omega-6 fatty
acids and an increased omega-6: omega-3 ratio may increase the risk of BD. This causal …

OBJECTIVES Previous work suggests supplementation with omega‐3 polyunsaturated fatty
acids (PUFAs) may improve mood symptoms in bipolar disorder (BD) although findings …

Background Nutraceuticals are a group of compounds of growing interest for mental health
professionals. Given the implication of certain nutrients in the onset of bipolar disorder, it has …

Objectives We performed a network meta-analysis (NMA) with up-to-date evidence to
compare different anti-inflammatory agents to improve the treatment of bipolar disorder (BD) …

Background: Treatments for depression in bipolar disorder (BD) are far less well developed
than for unipolar major depressive disorder. Several innovative and experimental …

Background: Inflammation is an important mechanism in the pathogenesis of delirium. Since
delirium might reduce by anti-inflammatory effects of omega-3 fatty acids. Based on this …