Mitochondria, metabolism, and redox mechanisms in psychiatric disorders

Y Kim, KC Vadodaria, Z Lenkei, T Kato… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Our current knowledge of the pathophysiology and molecular mechanisms
causing psychiatric disorders is modest, but genetic susceptibility and environmental factors …

Schizophrenia, bipolar and major depressive disorders: overview of clinical features, neurotransmitter alterations, pharmacological interventions, and impact of …

PK Mandal, S Gaur, RG Roy, A Samkaria… - ACS Chemical …, 2022 - ACS Publications
Psychiatric disorders are one of the leading causes of disability worldwide and affect the
quality of life of both individuals and the society. The current understanding of these …

Chemical analysis in saliva and the search for salivary biomarkers–a tutorial review

K Ngamchuea, K Chaisiwamongkhol… - Analyst, 2018 - pubs.rsc.org
Biomarkers refer to analytes that can be used in the diagnosis of diseases or disorders. In
saliva, there are many components that are potential biomarkers, and increasing research …

The emerging role of glutathione in Alzheimer's disease

S Saharan, PK Mandal - Journal of Alzheimer's Disease, 2014 - content.iospress.com
With millions of older individuals presently suffering from Alzheimer's disease (AD)
worldwide, AD is an unduly common form of dementia that exacts a heavy toll on affected …

Antioxidant defense in schizophrenia and bipolar disorder: A meta-analysis of MRS studies of anterior cingulate glutathione

TK Das, A Javadzadeh, A Dey, P Sabesan… - Progress in Neuro …, 2019 - Elsevier
Background Glutathione [GSH] is a major intracellular antioxidant that disposes peroxides
and protects neurons and glial cells from oxidative stress. In both schizophrenia and bipolar …

Design of a lab-on-chip for cancer cell detection through impedance and photoelectrochemical response analysis

YP Hsiao, A Mukundan, WC Chen, MT Wu, SC Hsieh… - Biosensors, 2022 - mdpi.com
In this study, a biochip was fabricated using a light-absorbing layer of a silicon solar element
combined with serrated, interdigitated electrodes and used to identify four different types of …

Oxidative stress markers in affective disorders

M Siwek, M Sowa-Kućma, D Dudek, K Styczeń… - Pharmacological …, 2013 - Elsevier
Affective disorders are a medical condition with a complex biological pattern of etiology,
involving genetic and epigenetic factors, along with different environmental stressors …

Molecular mechanisms of bipolar disorder: progress made and future challenges

Y Kim, R Santos, FH Gage… - Frontiers in cellular …, 2017 - frontiersin.org
Bipolar disorder (BD) is a chronic and progressive psychiatric illness characterized by mood
oscillations, with episodes of mania and depression. The impact of BD on patients can be …

[HTML][HTML] Deficits in episodic memory retrieval reveal impaired default mode network connectivity in amnestic mild cognitive impairment

CJ Dunn, SL Duffy, IB Hickie, J Lagopoulos… - NeuroImage: Clinical, 2014 - Elsevier
Amnestic mild cognitive impairment (aMCI) is believed to represent a transitional stage
between normal healthy ageing and the development of dementia. In particular, aMCI …

Neurochemistry of major depression: a study using magnetic resonance spectroscopy

BR Godlewska, J Near, PJ Cowen - Psychopharmacology, 2015 - Springer
Rationale Magnetic resonance spectroscopy (MRS) is an acceptable non-invasive means of
studying brain neurochemistry in depression. Previous studies in depressed patients have …