Circulating noncoding RNAs as biomarkers of cardiovascular disease and injury

J Viereck, T Thum - Circulation research, 2017 - Am Heart Assoc
The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …

MicroRNAs in heart failure: from biomarker to target for therapy

EL Vegter, P van der Meer, LJ de Windt… - European journal of …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …

Long noncoding RNAs and microRNAs in cardiovascular pathophysiology

T Thum, G Condorelli - Circulation research, 2015 - Am Heart Assoc
RNAs not encoding proteins have gained prominence over the last couple of decades as
fundamental regulators of cellular function. Not surprisingly, their dysregulation is …

microRNAs in cardiovascular diseases: current knowledge and the road ahead

G Condorelli, MVG Latronico, E Cavarretta - Journal of the American …, 2014 - jacc.org
Over the last few years, the field of microribonucleic acid (miRNA) in cardiovascular biology
and disease has expanded at an incredible pace. miRNAs are themselves part of a larger …

Heart-type fatty acid-binding protein (H-FABP) and its role as a biomarker in heart failure: what do we know so far?

R Rezar, P Jirak, M Gschwandtner, R Derler… - Journal of clinical …, 2020 - mdpi.com
Background: Heart failure (HF) remains one of the leading causes of death to date despite
extensive research funding. Various studies are conducted every year in an attempt to …

Overview of microRNAs in cardiac hypertrophy, fibrosis, and apoptosis

J Wang, OW Liew, AM Richards, YT Chen - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are non-coding RNAs that play essential roles in modulating the gene
expression in almost all biological events. In the past decade, the involvement of miRNAs in …

Circulating microRNA-122-5p is associated with a lack of improvement in left ventricular function after transcatheter aortic valve replacement and regulates viability of …

MR Hosen, PR Goody, A Zietzer, X Xiang… - Circulation, 2022 - Am Heart Assoc
Background: Transcatheter aortic valve replacement (TAVR) is a well-established treatment
option for high-and intermediate-risk patients with severe symptomatic aortic valve stenosis …

Novel invasive and noninvasive cardiac-specific biomarkers in obesity and cardiovascular diseases

R Parsanathan, SK Jain - Metabolic syndrome and related disorders, 2020 - liebertpub.com
Cardiovascular disease (CVD) is the leading cause of fatality and disability worldwide
regardless of gender. Obesity has reached epidemic proportions in population across …

MicroRNA as a therapeutic target in cardiac remodeling

C Chen, M Ponnusamy, C Liu, J Gao… - BioMed research …, 2017 - Wiley Online Library
MicroRNAs (miRNAs) are small RNA molecules that contain 18–25 nucleotides. The
alterations in their expression level play crucial role in the development of many disorders …

A change of heart: understanding the mechanisms regulating cardiac proliferation and metabolism before and after birth

CG Dimasi, JRT Darby… - The Journal of Physiology, 2023 - Wiley Online Library
Mammalian cardiomyocytes undergo major maturational changes in preparation for birth
and postnatal life. Immature cardiomyocytes contribute to cardiac growth via proliferation …