Apoptosis is a prominent feature of liver diseases. Causative factors such as alcohol,
viruses, toxic bile acids, fatty acids, drugs, and immune response, can induce apoptotic cell …

Currently, the most effective therapy for acute liver failure and advanced cirrhosis is liver
transplantation. However, this procedure has several limitations, including lack of donors …

Background: Pressure overload–induced pathological cardiac hypertrophy is a common
predecessor of heart failure, the latter of which remains a major cardiovascular disease with …

Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in
the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis is …

The intravenous injection of the plant lectin concanavalin A (ConA) is a widely used model
for acute immune-mediated hepatitis in mice. In contrast to several other models for acute …

Modified citrus pectin (MCP) has a low-molecular-weight degree of esterification to allow
absorption from the small intestinal epithelium into the circulation. MCP produces pleiotropic …

Galectin-3 (gal-3) is a β-galactoside-binding lectin, which regulates cell–cell and
extracellular interactions during self/non-self-antigen recognition and cellular activation …

Obesity-induced diabetes is associated with low-grade inflammation in adipose tissue and
macrophage infiltration of islets. We show that ablation of galectin-3 (Gal-3), a galactoside …

Ulcerative colitis (UC) is an inflammatory bowel disease that affects the colon and rectum.
Although galectin-3 (Gal-3) has been reported to play a proinflammatory role in UC, it is …

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by
a wide variety of cells and bind to galactose-containing glycans. Galectins can be located in …