All organisms have evolved several defence systems in order to protect themselves against
bacteria, fungi and viruses. Higher organisms have developed a complex network of …

RNase T1 is the best known representative of a large family of ribonucleolytic proteins
secreted by fungi, mostly Aspergillus and Penicillium species. Ribotoxins stand out among …

α‐Sarcin is a ribosome‐inactivating protein that has been well characterized in vitro, but little
is known about its toxicity in living cells. We have analyzed the mechanism of internalization …

Fungi establish a complex network of biological interactions with other organisms in nature.
In many cases, these involve the production of toxins for survival or colonization purposes …

We investigated the inhibitory effects of the antifungal protein (AFP) from Aspergillus
giganteus on the growth of several filamentous fungi. For this purpose, the MICs of AFP were …

Antivirals are compounds used since the 1960s that can interfere with viral development.
Some of these antivirals can be isolated from a variety of sources, such as animals, plants …

Antifungal proteins produced by molds are generally small, highly basic, and cysteine-rich.
The best known effects of these proteins include morphological changes, metabolic …

A single-chain fusion protein that directed the cytolytic activity of α-sarcin to A33 tumor
antigen expressing cells was constructed and shown to effectively kill targeted cells …

Elsewhere in this volume, 1 it was mentioned that it would be interesting to insert the
targeting motifs of ribotoxins (presumably responsible for the ability to gain access to the …

The mold Aspergillus giganteus produces a basic, low molecular weight protein showing
antifungal properties against economically important plant pathogens, the AFP (A nti f ungal …