Nature gifts medicinal plants with the untapped and boundless treasure of active chemical
constituents with significant therapeutic potential that makes these plants a beneficial source …

Neuropathic pain is a complex, chronic pain state accompanied by tissue injury and nerve
damage. This important health issue constitutes a challenge for the modern medicine …

Melting points were determined on a Yanaco MP-500 micro melting point apparatus and
were uncorrected. Infrared spectra were measured with a Nicolet Avatar 360 FT-IR …

The methanolic extract of umbu (Spondias tuberosa) presented high antioxidant activities in
the DPPH, ABTS and ORAC assays, as well as acetylcholinesterase (AChE) inhibition …

Natural products have been revealed as relevant sources of therapeutic agents including
those for the management of pain states. In this study, the anti-nociceptive and anti …

The genus Cassia, comprising about 600 species widely distributed worldwide is well
known for its diverse biological and pharmacological properties. Cassia spectabilis (sin …

Senna spectabilis (sin. Cassia excelsa, C. spectabilis) is an endemic tree of South America
and Africa, very common in Brazil, where it is known as “canafistula-de-besouro” and “cassia …

Leishmaniasis is one of the most important neglected tropical diseases (NTDs) that are
especially common among low-income populations in developing regions of Africa, Asia …

In our continuing work looking for new anti-infective lead compounds from Brazilian biomes,
the two known piperidine alkaloids (-)-cassine and (-)-spectaline were isolated from the …

Several species of Senna are well known for their therapeutic properties, being used in folk
medicine to treat throat inflammation and constipation. In this regard, the anti-inflammatory …