Etiology and therapeutic approach to elevated lactate levels
LW Andersen, J Mackenhauer, JC Roberts… - Mayo Clinic …, 2013 - Elsevier
Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …
the context of evaluating shock, lactate levels can be elevated for many reasons. While …
Using IL-6 concentrations in the first 24 h following trauma to predict immunological complications and mortality in trauma patients: a meta-analysis
Z Qiao, W Wang, L Yin, P Luo, J Greven, K Horst… - European journal of …, 2018 - Springer
Purpose In previous studies, interleukin-6 (IL-6) has been shown to have a high predictive
value for the development of complications and mortality after trauma; however, there is …
value for the development of complications and mortality after trauma; however, there is …
[HTML][HTML] L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis
KS Kamel, MS Oh, ML Halperin - Kidney International, 2020 - Elsevier
L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care
setting, which has been associated with a large increase in mortality. The purpose of this …
setting, which has been associated with a large increase in mortality. The purpose of this …
[HTML][HTML] Lactate as a diagnostic marker in transient loss of consciousness
O Matz, C Zdebik, S Zechbauer, L Bündgens… - Seizure, 2016 - Elsevier
Purpose The diagnostic classification of disorders of consciousness is often challenging,
particularly the distinction between epileptic and non-epileptic seizures. The aim of the study …
particularly the distinction between epileptic and non-epileptic seizures. The aim of the study …
The effect of recombinant erythropoietin on long-term outcome after moderate-to-severe traumatic brain injury
Purpose Recombinant erythropoietin (EPO) administered for traumatic brain injury (TBI) may
increase short-term survival, but the long-term effect is unknown. Methods We conducted a …
increase short-term survival, but the long-term effect is unknown. Methods We conducted a …
Very early posttraumatic serum alterations are significantly associated to initial massive RBC substitution, injury severity, multiple organ failure and adverse clinical …
Background Multiple severe trauma frequently leads to massive dysbalances of the human
immune system. This phenomenon is known as" Systemic Inflammatory Response …
immune system. This phenomenon is known as" Systemic Inflammatory Response …
Prehospital hypotension is associated with altered inflammation dynamics and worse outcomes following blunt trauma in humans
Objective: To define the impact of prehospital hypotension on the dynamic, systemic acute
inflammatory response to blunt trauma. Design: Retrospective study. Settings: Tertiary care …
inflammatory response to blunt trauma. Design: Retrospective study. Settings: Tertiary care …
Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries
Extremity and soft tissue injuries contribute significantly to inflammation and adverse in-
hospital outcomes for trauma survivors; accordingly, we examined the complex association …
hospital outcomes for trauma survivors; accordingly, we examined the complex association …
Increased enzymatic activity of acetylcholinesterase indicates the severity of the sterile inflammation and predicts patient outcome following traumatic injury
AR Zivkovic, GM Paul, S Hofer, K Schmidt, T Brenner… - Biomolecules, 2023 - mdpi.com
Traumatic injury induces sterile inflammation, an immune response often associated with
severe organ dysfunction. The cholinergic system acts as an anti-inflammatory in injured …
severe organ dysfunction. The cholinergic system acts as an anti-inflammatory in injured …
Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic–clonic seizures from syncopes
O Matz, J Heckelmann, S Zechbauer, J Litmathe… - Internal and Emergency …, 2018 - Springer
Concentrations of serum creatine kinase (CK) and serum lactate are frequently measured to
help differentiate between generalized tonic–clonic seizures (GTCS) and syncope. The aim …
help differentiate between generalized tonic–clonic seizures (GTCS) and syncope. The aim …