Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …

Reactive oxygen species (ROS) represent a group of high reactive molecules with dualistic
natures since they can induce cytotoxicity or regulate cellular physiology. Among the ROS …

Cancer is a huge challenge for people worldwide. High reactive oxygen species (ROS)
levels are a recognized hallmark of cancer and an important aspect of cancer treatment …

The effective treatment of acute myeloid leukemia (AML) is very challenging. Due to the
immense heterogeneity of this disease, treating it using a “one size fits all” approach is …

Reactive oxygen species (ROS; eg., superoxide [O2•−] and hydrogen peroxide [H2O2]) and
reactive nitrogen species (RNS; eg., nitric oxide [NO•]) at the physiological level function as …

Reprogrammed metabolism and high energy demand are well-established properties of
cancer cells that enable tumor growth. Glycolysis is a primary metabolic pathway that …

Reactive oxygen species (ROS), previously considered toxic by-products of aerobic
metabolism, are increasingly recognized as regulators of cellular signaling. Keeping ROS …

One-carbon metabolism provides the methyl groups for both DNA and histone tail
methylation reactions, two of the main epigenetic processes that tightly regulate the …

Nanozyme catalytic therapy for cancer treatments has become one of the heated topics, and
the therapeutic efficacy is highly correlated with their catalytic efficiency. In this work, three …

Abnormal energy metabolism, as one of the important hallmarks of cancer, was induced by
multiple carcinogenic factors and tumor-specific microenvironments. It comprises aerobic …