The Pol III transcriptome: basic features, recurrent patterns, and emerging roles in cancer
S Zhou, K Van Bortle - Wiley Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short,
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …
The POLR3G subunit of human RNA polymerase III regulates tumorigenesis and metastasis in triple-negative breast cancer
W Lautré, E Richard, JP Feugeas, H Dumay-Odelot… - Cancers, 2022 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) does not express estrogen or
progesterone hormone receptors and does not overexpress the HER2 transmembrane …
progesterone hormone receptors and does not overexpress the HER2 transmembrane …
Regulation of bacterial gene expression by non-coding RNA: It is all about time!
A Chauvier, NG Walter - Cell Chemical Biology, 2024 - cell.com
Commensal and pathogenic bacteria continuously evolve to survive in diverse ecological
niches by efficiently coordinating gene expression levels in their ever-changing …
niches by efficiently coordinating gene expression levels in their ever-changing …
The subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type
T Cherlin, Y Jing, S Shah, A Kennedy, AG Telonis… - BMC biology, 2024 - Springer
Abstract Background MicroRNA isoforms (isomiRs), tRNA-derived fragments (tRFs), and
rRNA-derived fragments (rRFs) represent most of the small non-coding RNAs (sncRNAs) …
rRNA-derived fragments (rRFs) represent most of the small non-coding RNAs (sncRNAs) …
[HTML][HTML] Regulating POLR3G by MicroRNA-26a-5p as a promising therapeutic target of lung cancer stemness and chemosensitivity
CR Park, M Lee, SY Lee, D Kang, SJ Park… - Non-coding RNA …, 2023 - Elsevier
Cancer stem cells (CSCs) identified in lung cancer exhibit resistance to chemotherapy,
radiotherapy, and targeted therapy. Therefore, a technology for controlling CSCs is needed …
radiotherapy, and targeted therapy. Therefore, a technology for controlling CSCs is needed …
Selection of tRNA Genes in Human Breast Tumours Varies Substantially between Individuals
Simple Summary Elevated expression of many tRNAs is a consistent feature of breast
cancer. As each tRNA is encoded by multiple genes, we investigate whether the same …
cancer. As each tRNA is encoded by multiple genes, we investigate whether the same …
The role of B cells in the pathogenesis of systemic sclerosis: an update
LI Sakkas, CG Katsiari, D Daoussis… - Rheumatology, 2023 - academic.oup.com
The pathogenesis of SSc is incompletely understood, but several lines of evidence suggest
that B cells are involved. Effector B (Beff) cells are hyperactivated and produce …
that B cells are involved. Effector B (Beff) cells are hyperactivated and produce …
POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer
H Chen, L Ma, W Yang, Y Li, Z Ji - The FASEB Journal, 2023 - Wiley Online Library
Abstract RNA Polymerase III Subunit G (POLR3G) promotes tumorigenesis, metastasis,
cancer stemness, and chemoresistance of breast cancer and lung cancer; however, its …
cancer stemness, and chemoresistance of breast cancer and lung cancer; however, its …
RNA polymerase III transcription and cancer: A tale of two RPC7 subunits
R Cheng, K Van Bortle - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
RNA polymerase III composition is shaped by the mutually exclusive incorporation of two
paralogous subunits, RPC7α and RPC7β, encoded by genes POLR3G and POLR3GL in …
paralogous subunits, RPC7α and RPC7β, encoded by genes POLR3G and POLR3GL in …