Recent advances in biological production of 3-hydroxypropionic acid

V Kumar, S Ashok, S Park - Biotechnology advances, 2013 - Elsevier
Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

V Kumar, S Park - Biotechnology advances, 2018 - Elsevier
Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol
efficiently under both aerobic and anaerobic conditions. This microbe is considered an …

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

XR Jiang, X Yan, LP Yu, XY Liu, GQ Chen - Nature communications, 2021 - nature.com
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Metabolic engineering of Corynebacterium glutamicum for the production of 3-hydroxypropionic acid from glucose and xylose

Z Chen, J Huang, Y Wu, W Wu, Y Zhang, D Liu - Metabolic Engineering, 2017 - Elsevier
Hydroxypropionic acid (3-HP) is a promising platform chemical which can be used for the
production of various value-added chemicals. In this study, Corynebacterium glutamicum …

Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae

Y Chen, J Bao, IK Kim, V Siewers, J Nielsen - Metabolic engineering, 2014 - Elsevier
Hydroxypropionic acid (3-HP) is an attractive platform chemical, which can be used to
produce a variety of commodity chemicals, such as acrylic acid and acrylamide. For …

Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

Z Chen, D Liu - Biotechnology for biofuels, 2016 - Springer
As an inevitable by-product of the biofuel industry, glycerol is becoming an attractive
feedstock for biorefinery due to its abundance, low price and high degree of reduction …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Bio-based 3-hydroxypropionic-and acrylic acid production from biodiesel glycerol via integrated microbial and chemical catalysis

T Dishisha, SH Pyo, R Hatti-Kaul - Microbial Cell Factories, 2015 - Springer
Abstract Background 3-Hydroxypropionic acid (3HP) and acrylic acid (AA) are industrially
important platform-and secondary chemical, respectively. Their production from renewable …

Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks

Y Chen, J Nielsen - Current opinion in biotechnology, 2013 - Elsevier
Highlights•Microbial production of chemicals is an attractive alternative to chemical
synthesis.•An integrated approach would be required to construct robust microbial chemical …