First experimental demonstration of real-time neutron capture discrimination in helium and carbon ion therapy

M Kielly, A Caracciolo, A Chacon, J Vohradsky… - Scientific Reports, 2024 - nature.com
This work provides the first experimental proof of an increased neutron capture photon
signal following the introduction of boron to a PMMA phantom during helium and carbon ion …

A spectroscopic and imaging gamma-detector prototype towards dose monitoring in BNCT

A Caracciolo, D Di Vita, T Ferri, M Carminati… - Nuclear Instruments and …, 2023 - Elsevier
We report the performances of a compact gamma-ray detection prototype, based on a 2”
LaBr 3 scintillator crystal coupled to a matrix of 64 SiPMs, designed as a single unit for a …

Gamma-Ray Position-of-Interaction Estimation in a Thick Monolithic LaBr3 Detector Using Artificial Neural Networks

T Ferri, F Rosellini, A Caracciolo… - … on Radiation and …, 2024 - ieeexplore.ieee.org
Monolithic gamma-ray detectors can be used in SPECT systems for monitoring the delivered
dose during Boron Neutron Capture Therapy treatments. Gamma-ray hit localization in thick …

An exploratory study of shielding strategies for boron neutron capture discrimination in 10B Neutron Capture Enhanced Particle Therapy

M Kielly, A Chacon, A Caracciolo, D Bolst, A Rosenfeld… - Physica Medica, 2025 - Elsevier
Purpose: To evaluate the impact of a range of shielding strategies on the rate of false
positive detections by a simulated detector for application in Neutron Capture Enhanced …

Prompt-gamma imaging in particle therapy

P Magalhaes Martins, E Draeger, A Wrońska - Frontiers in Physics, 2024 - frontiersin.org
Prompt gamma imaging (PGI) is a promising technique to tackle range uncertainties in
particle therapy with protons, helium and carbon ions. Several concepts have been …

A feasibility study using an array of LaBr3(Ce) scintillation detectors as a Compton camera for prompt gamma imaging during BNCT

K Nutter, T Price, T Kokalova, S Green… - Frontiers in …, 2024 - frontiersin.org
Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy where a low energy
neutron beam is incident upon a patient who has been administered a tumour-seeking 10B …

[HTML][HTML] A compact scintillator-based detector with collimator and shielding for dose monitoring in boron neutron capture therapy

A Caracciolo, T Ferri, G Borghi, M Carminati… - Physics and Imaging in …, 2024 - Elsevier
Boron neutron capture therapy exploits 10 B (n, α) 7 Li reactions for targeted tumor
destruction. In this work, we aimed at developing a dose monitoring system based on the …

Compact pixelated scintillator detector investigation for gamma ray detection

JL Wang, XG Wu, ZY He, LW Yang… - Engineering …, 2024 - iopscience.iop.org
Objective. A scintillator is a luminescent material that converts high-energy photons into
visible light and is widely used in medical imaging. Different scintillators are applied to …

Study of the thermal neutron activation of a gamma-ray detector for BNCT dose monitoring

G Colombo, A Caracciolo, D Mazzucconi… - Journal of …, 2024 - iopscience.iop.org
We present a study on the neutron activation of a gamma-ray detector for a BNCT-SPECT
dose imaging system. The detector is based on a LaBr 3 (Ce+ Sr) scintillator crystal, coupled …

Imaging Study and First Measurements of a LaBr3 Gamma Detector for BNCT Applications

T Ferri, A Caracciolo, G Borghi… - … on Nuclear Science, 2024 - ieeexplore.ieee.org
In this study, we present the preliminary imaging results obtained with a gamma module
called BeNEdiCTE, specifically designed for boron neutron capture therapy (BNCT). The …