Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …

Abstract The European Collaborative on Personalized Early Detection and Prevention of
Breast Cancer (ENVISION) brings together several international research consortia working …

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants …

PURPOSE To develop recommendations for management of patients with breast cancer
(BC) with germline mutations in BC susceptibility genes. METHODS The American Society …

Background Women with a BRCA1 or BRCA2 mutation face high risks of breast and ovarian
cancer. In the current study, we report on uptake of cancer screening and risk-reduction …

Women who inherit a deleterious BRCA1 or BRCA2 mutation face substantially increased
risks of developing breast cancer, which is estimated at 70%. Although annual screening …

Purpose Indications for nipple-sparing mastectomy (NSM) have broadened to include the
risk reducing setting and locally advanced tumors, which resulted in a dramatic increase in …

Background Implant-based breast reconstruction (IBBR) remains the standard and most
popular option for women undergoing breast reconstruction after mastectomy worldwide …

Introduction Nipple-sparing mastectomy (NSM) is increasingly used for breast cancer risk
reduction and treatment. Prior small studies with variable control for baseline characteristics …

Transgender men or Female-to-Male (FtM) patients' risk of breast cancer and screening
recommendations remain unclear. The objective of this study is to perform a systematic …