Using photo-initiated polymerization reactions to detect molecular recognition

K Kaastrup, HD Sikes - Chemical Society Reviews, 2016 - pubs.rsc.org
Widely used medical diagnostic devices and assays that sense the presence of a particular
molecule in a bodily fluid often rely on either a nanoparticle label or an enzymatic reaction to …

Light microscopy of proteins in their ultrastructural context

O M'Saad, J Bewersdorf - Nature communications, 2020 - nature.com
Resolving the distribution of specific proteins at the nanoscale in the ultrastructural context of
the cell is a major challenge in fluorescence microscopy. We report the discovery of a new …

Switchable DNA Photocatalysts for Radical Polymerization Controlled by Chemical Stimuli

CA Cox, AN Ogorek, JP Habumugisha… - Journal of the …, 2023 - ACS Publications
Polymerization catalysts that activate in response to specific chemical triggers offer spatial
and temporal control over polymer synthesis, facilitating the development of responsive …

Coatings on mammalian cells: interfacing cells with their environment

KA Davis, PJ Wu, CF Cahall, C Li, A Gottipati… - Journal of biological …, 2019 - Springer
The research community is intent on harnessing increasingly complex biological building
blocks. At present, cells represent a highly functional component for integration into higher …

Characterization of molecular transport in ultrathin hydrogel coatings for cellular immunoprotection

JL Lilly, G Romero, W Xu, HY Shin… - Biomacromolecules, 2015 - ACS Publications
PEG hydrogels are routinely used in immunoprotection applications to hide foreign cells
from a host immune system. Size-dependent transport is typically exploited in these systems …

Comparison of eosin and fluorescein conjugates for the photoinitiation of cell-compatible polymer coatings

JL Lilly, A Gottipati, CF Cahall, M Agoub, BJ Berron - PloS one, 2018 - journals.plos.org
Targeted photopolymerization is the basis for multiple diagnostic and cell encapsulation
technologies. While eosin is used in conjunction with tertiary amines as a water-soluble …

LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1

Z Wang, S Zhang, Y Li, R Wang, L Tong… - Acta Pharmacologica …, 2017 - nature.com
Glomerular endothelial cell (GEC) injury plays an important role in the early stage of diabetic
nephropathy (DN). Previous studies show that a PKCβ inhibitor is effective for treating DN. In …

Genetically encoded stimuli-responsive cytoprotective hydrogel capsules for single cells provide novel genotype–phenotype linkage

R Vanella, A Bazin, DT Ta, MA Nash - Chemistry of Materials, 2019 - ACS Publications
Modification of cell surfaces with synthetic polymers is a promising approach for regulating
cellular behavior. Here, we describe a genetically controlled strategy for selectively …

Protective polymer coatings for high-throughput, high-purity cellular isolation

G Romero, JJ Lilly, NS Abraham, HY Shin… - … Applied Materials & …, 2015 - ACS Publications
Cell-based therapies are emerging as the next frontier of medicine, offering a plausible path
forward in the treatment of many devastating diseases. Critically, current methods for antigen …

Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays

JK Lee, BW Heimer, HD Sikes - Biomacromolecules, 2012 - ACS Publications
We report a systematic investigation of a set of photoreducible macrophotoinitiators for use
in polymerization-based signal amplification. To test the dependence of photopolymerization …