Immunomodulatory effects of dietary polyphenols

H Shakoor, J Feehan, V Apostolopoulos, C Platat… - Nutrients, 2021 - mdpi.com
Functional and nutraceutical foods provide an alternative way to improve immune function to
aid in the management of various diseases. Traditionally, many medicinal products have …

Polyphenols in the treatment of autoimmune diseases

H Khan, A Sureda, T Belwal, S Çetinkaya, İ Süntar… - Autoimmunity …, 2019 - Elsevier
In addition to protecting body from infections and diseases, the immune system produces
auto-antibodies that can cause complex autoimmune disorders, such as Type I diabetes …

Effects of flavonoids and other polyphenols on inflammation

R González, I Ballester, R López-Posadas… - Critical reviews in …, 2011 - Taylor & Francis
Flavonoids are a family of polyphenolic compounds which are widespread in nature
(vegetables) and are consumed as part of the human diet in significant amounts. There are …

Inflammation in metabolic cardiomyopathy

FA Wenzl, S Ambrosini, SA Mohammed… - Frontiers in …, 2021 - frontiersin.org
Overlapping pandemics of lifestyle-related diseases pose a substantial threat to
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …

Resveratrol: its biologic targets and functional activity

S Pervaiz, AL Holme - Antioxidants & redox signaling, 2009 - liebertpub.com
Abstract 2852 The polyphenolic phytoalexin resveratrol (RSV) and its analogues have
received tremendous attention over the past couple of decades because of a number of …

The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS …

S Sukhanov, Y Higashi, T Yoshida, S Mummidi… - Cellular signalling, 2021 - Elsevier
Chronic inflammation and persistent oxidative stress contribute to the development and
progression of vascular proliferative diseases. We hypothesized that the proinflammatory …

Molecular basis of the beneficial actions of resveratrol

G Repossi, UN Das, AR Eynard - Archives of medical research, 2020 - Elsevier
Resveratrol modulates the transcription factor NF-κB, cytochrome P450 isoenzyme CYP1A1,
expression and activity of cyclooxygenase (COX) enzymes, Fas/Fas ligand mediated …

Effects of Interleukin 17 on the cardiovascular system

M Robert, P Miossec - Autoimmunity reviews, 2017 - Elsevier
Cardiovascular diseases remain the leading cause of death worldwide and account for most
of the premature mortality observed in chronic inflammatory diseases. Common …

Exploring the role of polyphenols in rheumatoid arthritis

T Behl, K Mehta, A Sehgal, S Singh… - Critical Reviews in …, 2022 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic, inflammatory and autoimmune disorder which is
mainly characterized by inflammation in joints, bone erosions and cartilaginous destruction …

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease

ME Truchetet, NC Brembilla, E Montanari… - Arthritis research & …, 2011 - Springer
Introduction T cell abnormalities have been associated with the pathogenesis of systemic
sclerosis (SSc). Recently, besides T helper (Th) 17 cells, the Th22 subset has been …