Progressive noradrenergic degeneration and motor cortical dysfunction in Parkinson's disease
W Zhou, HY Chu - Acta Pharmacologica Sinica, 2024 - nature.com
The locus coeruleus norepinephrine (LC-NE) system plays an important role in regulating
brain function, and its neuronal loss has been well-documented in Parkinson's disease (PD) …
brain function, and its neuronal loss has been well-documented in Parkinson's disease (PD) …
[HTML][HTML] β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction
Uncontrollable stress exposure impairs working memory and reduces the firing of
dorsolateral prefrontal cortex (dlPFC)“Delay cells”, involving high levels of norepinephrine …
dorsolateral prefrontal cortex (dlPFC)“Delay cells”, involving high levels of norepinephrine …
Acute vagus nerve stimulation enhances reversal learning in rats
LKP Altidor, MM Bruner, JF Deslauriers… - Neurobiology of learning …, 2021 - Elsevier
Cognitive flexibility is a prefrontal cortex-dependent neurocognitive process that enables
behavioral adaptation in response to changes in environmental contingencies. Electrical …
behavioral adaptation in response to changes in environmental contingencies. Electrical …
[HTML][HTML] Noradrenergic mechanisms and circuitry of hyperkatifeia in alcohol use disorder
Hyperkatifeia, the manifestation of emotional distress or pain, is a conceptual framework
gaining traction throughout the alcohol and other substance use fields as an important driver …
gaining traction throughout the alcohol and other substance use fields as an important driver …
Effect of 17β‐oestradiol on T‐type calcium channels in the lateral habenula
MY Song, CY Li, XF Liu, JY Xiao… - Journal of …, 2018 - Wiley Online Library
T‐type calcium channels (T‐channels) are critical for regulating neuronal excitability.
Oestrogen alters neuronal excitability by modulating the expression of T‐channels. The …
Oestrogen alters neuronal excitability by modulating the expression of T‐channels. The …
GABAB receptors in the hypothalamic paraventricular nucleus mediate β-adrenoceptor-induced elevations of plasma noradrenaline in rats
N Yamaguchi, K Mimura, S Okada - European Journal of Pharmacology, 2019 - Elsevier
In the brain, various neurotransmitters such as noradrenaline and GABA regulate peripheral
sympathetic functions. Previously, it has been reported that both β-adrenoceptor activation …
sympathetic functions. Previously, it has been reported that both β-adrenoceptor activation …
Beta-adrenergic receptor activation increases GABA uptake in adolescent mice frontal cortex: Modulation by cannabinoid receptor agonist WIN55, 212-2
RS Martins, IG De Freitas, MF Sathler… - Neurochemistry …, 2018 - Elsevier
GABA transporters regulate synaptic GABA levels and dysfunctions in this system might
result in psychiatric disorders. The endocannabinoid system (ECS) is the main circuit …
result in psychiatric disorders. The endocannabinoid system (ECS) is the main circuit …
L-type Ca2+ channels and charybdotoxin-sensitive Ca2+-activated K+ channels are required for reduction of GABAergic activity induced by β2-adrenoceptor in the …
WK Deng, X Wang, HC Zhou, F Luo - Molecular and Cellular Neuroscience, 2019 - Elsevier
Abstract Whereas β2-adrenoceptor (β2-AR) has been reported to reduce GABAergic activity
in the prefrontal cortex (PFC), the underlying cellular and molecular mechanisms have not …
in the prefrontal cortex (PFC), the underlying cellular and molecular mechanisms have not …
Estudio de los efectos de la actividad constitutiva del receptor de dopamina tipo 1 (D1R) sobre los canales de calcio operados por voltaje (CaV) y su rol en neuronas …
CI McCarthy - 2022 - sedici.unlp.edu.ar
Las neuronas de la corteza prefrontal (CPF) tienen una abundante inervación
dopaminérgica y expresan altos niveles de receptores para dopamina. Numerosas …
dopaminérgica y expresan altos niveles de receptores para dopamina. Numerosas …