Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …

Translation of cardioprotective interventions aimed at reducing myocardial injury during
ischaemia–reperfusion from experimental studies to clinical practice is an important yet …

Preserving mitochondrial activity is crucial in rescuing cardiac function following acute
myocardial ischemia/reperfusion (I/R). The sex difference in myocardial functional recovery …

Ischemia and reperfusion (I/R) cause a reduction in arterial blood supply to tissues, followed
by the restoration of perfusion and consequent reoxygenation. The reestablishment of blood …

We determined the impact of sex on the magnitude of cardioprotection by local and remote
ischemic preconditioning (IPC and RIPC) and of ischemic/reperfused peripheral tissue mass …

Background Uremic cardiomyopathy is a common cardiovascular complication of chronic
kidney disease (CKD) characterized by left ventricular hypertrophy (LVH) and fibrosis …

Phthalate plasticizers are ubiquitous chemicals linked to several cardiovascular diseases in
animal models and humans. Despite this, the mechanisms by which phthalate exposures …

Ischaemic post‐conditioning (IPoC) is a clinical applicable procedure to reduce reperfusion
injury. Non‐responsiveness to IPoC possibly caused by co‐morbidities limits its clinical …

During menopause women are exposed to an increase in cardiovascular risk. G protein-
coupled estrogen receptor (GPER) is known to mediate several of the protective effects of …

Experimentally, many strong cardioprotective treatments have been identified in different
animal models of acute ischaemia/reperfusion injury (IRI) and coronary artery disease …