Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

In most eukaryotes, the kinetochore protein complex assembles at a single locus termed the
centromere to attach chromosomes to spindle microtubules. Holocentric chromosomes have …

Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

During eukaryotic cell division, the sister chromatids of duplicated chromosomes are pulled
apart by microtubules, which connect via kinetochores. The kinetochore is a multiprotein …

The kinetochore is the macromolecular protein complex that directs chromosome
segregation in eukaryotes. It has been widely assumed that the core kinetochore consists of …

The point of attachment of spindle microtubules to metaphase chromosomes is known as the
centromere. Plant and animal centromeres are epigenetically specified by a centromere …

Dictyostelium discoideum (DD), an extensively studied model organism for cell and
developmental biology, belongs to the most derived group 4 of social amoebas, a clade of …

Semi-conservative segregation of nucleosomes to sister chromatids during DNA replication
creates gaps that must be filled by new nucleosome assembly. We analyzed the cell-cycle …

Although serine ADP-ribosylation (Ser-ADPr) by Poly (ADP-ribose)-polymerases is a
cornerstone of the DNA damage response, how this regulates DNA repair and genome …

Nuclear three dimensional (3D) folding of chromatin structure has been linked to gene
expression regulation and correct developmental programs, but little is known about the 3D …