A comprehensive review on selenium and its effects on human health and distribution in middle eastern countries

M Kieliszek, I Bano, H Zare - Biological Trace Element Research, 2022 - Springer
Selenium (Se) is an important microelement with numerous positive effects on human health
and diseases. It is important to specify that the status and consumption of Se are for a …

Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]‐gingerol in cancer: A comprehensive review

RMT de Lima, AC Dos Reis… - Phytotherapy …, 2018 - Wiley Online Library
Natural dietary agents have attracted considerable attention due to their role in promoting
health and reducing the risk of diseases including cancer. Ginger, one of the most ancient …

Selenium in cancer prevention: a review of the evidence and mechanism of action

MP Rayman - Proceedings of the Nutrition Society, 2005 - cambridge.org
Se is an unusual trace element in having its own codon in mRNA that specifies its insertion
into selenoproteins as selenocysteine (SeCys), by means of a mechanism requiring a large …

Antitumor effects of selenium

SJ Kim, MC Choi, JM Park, AS Chung - International Journal of Molecular …, 2021 - mdpi.com
Functions of selenium are diverse as antioxidant, anti-inflammation, increased immunity,
reduced cancer incidence, blocking tumor invasion and metastasis, and further clinical …

[HTML][HTML] Therapeutic enzyme-responsive nanoparticles for targeted delivery and accumulation in tumors

CE Callmann, CV Barback, MP Thompson… - … (Deerfield Beach, Fla …, 2015 - ncbi.nlm.nih.gov
In this Communication, we describe an enzyme-responsive, paclitaxel-loaded nanoparticle
and assess its safety and efficacy in vivo in a human fibrosarcoma murine xenograft. The …

Food sources of selenium and its relationship with chronic diseases

W Hu, C Zhao, H Hu, S Yin - Nutrients, 2021 - mdpi.com
Selenium (Se) is an essential micronutrient for mammals, and its deficiency seriously
threatens human health. A series of biofortification strategies have been developed to …

Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

H Zeng, GF Combs Jr - The Journal of nutritional biochemistry, 2008 - Elsevier
Selenium is an essential dietary component for animals including humans, and there is
increasing evidence for the efficacy of certain forms of selenium as cancer-chemopreventive …

Glutathione peroxidases in different stages of carcinogenesis

R Brigelius-Flohe, A Kipp - Biochimica et Biophysica Acta (BBA)-General …, 2009 - Elsevier
Cancer cells produce high amounts of reactive oxygen species (ROS) and evade apoptosis.
Hydroperoxides support proliferation, invasion, migration and angiogenesis, but at higher …

Selenium, oxidative stress, and health aspects

P Brenneisen, H Steinbrenner, H Sies - Molecular aspects of medicine, 2005 - Elsevier
Metabolic processes which generate oxidants and antioxidants are governed by genetic
disposition as well as environmental factors. Changes in lifestyle, including increased …

[HTML][HTML] Roles of matrix metalloproteinases in tumor metastasis and angiogenesis

SO Yoon, SJ Park, CH Yun, AS Chung - BMB Reports, 2003 - koreascience.kr
Matrix metalloproteinases (MMPs), zinc dependent proteolytic enzymes, cleave extracellular
matrix (ECM: collagen, laminin, firbronectin, etc) as well as non-matrix substrates (growth …