Treatment of late sequelae after radiotherapy for head and neck cancer

P Strojan, KA Hutcheson, A Eisbruch, JJ Beitler… - Cancer treatment …, 2017 - Elsevier
Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

Image-guided radiotherapy: from current concept to future perspectives

DA Jaffray - Nature reviews Clinical oncology, 2012 - nature.com
Radiotherapy is a highly effective, targeted therapy for the management of cancer.
Technological innovations have enabled the direct integration of imaging technology into …

Use of larynx-preservation strategies in the treatment of laryngeal cancer: American Society of Clinical Oncology clinical practice guideline update

AA Forastiere, N Ismaila, JS Lewin… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To update the guideline recommendations on the use of larynx-preservation
strategies in the treatment of laryngeal cancer. Methods An Expert Panel updated the …

E1308: phase II trial of induction chemotherapy followed by reduced-dose radiation and weekly cetuximab in patients with HPV-associated resectable squamous cell …

S Marur, S Li, AJ Cmelak, ML Gillison… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma
(OPSCC) is treatment-responsive. Definitive chemoradiation results in high cure rates but …

A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the …

G Peng, T Wang, K Yang, S Zhang, T Zhang… - Radiotherapy and …, 2012 - Elsevier
BACKGROUND AND PURPOSE: To compare clinical outcomes and toxicities of two-
dimensional conventional radiation therapy (2D-CRT) and intensity modulated radiation …

[HTML][HTML] Radiotherapy side effects: integrating a survivorship clinical lens to better serve patients

V Dilalla, G Chaput, T Williams, K Sultanem - Current Oncology, 2020 - ncbi.nlm.nih.gov
Abstract The Canadian Cancer Society estimated that 220,400 new cases of cancer would
be diagnosed in 2019. Of the affected patients, more than 60% will survive for 5 years or …

Dysphagia-optimised intensity-modulated radiotherapy versus standard intensity-modulated radiotherapy in patients with head and neck cancer (DARS): a phase 3 …

C Nutting, L Finneran, J Roe, MA Sydenham… - The Lancet …, 2023 - thelancet.com
Background Most newly diagnosed oropharyngeal and hypopharyngeal cancers are treated
with chemoradiotherapy with curative intent but at the consequence of adverse effects on …

Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

M Machtay, J Moughan, A Trotti, AS Garden… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Concurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head
and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates …

Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy

JA Langendijk, P Doornaert… - Journal of clinical …, 2008 - ascopubs.org
Purpose To investigate the impact of treatment-related toxicity on health-related quality of life
(HRQoL) among patients with head and neck squamous cell carcinoma treated with …

Pathophysiology of radiation-induced dysphagia in head and neck cancer

SN King, NE Dunlap, PA Tennant, T Pitts - Dysphagia, 2016 - Springer
Oncologic treatments, such as curative radiotherapy and chemoradiation, for head and neck
cancer can cause long-term swallowing impairments (dysphagia) that negatively impact …