Management and prevention of Neisseria meningitidis and Neisseria gonorrhoeae infections in the context of evolving antimicrobial resistance trends

HS Marshall, JM Molina, V Berlaimont… - European Journal of …, 2024 - Springer
Purpose To describe the relationships between Neisseria meningitidis (NM) and Neisseria
gonorrhoeae (NG) at genetic, population, and individual levels; to review historical trends in …

Unveiling host–parasite relationships through conserved MITEs in prokaryote and viral genomes

F Nadal-Molero, R Rosselli, S Garcia-Juan… - Nucleic Acids …, 2024 - academic.oup.com
Transposable elements (TEs) play a pivotal role in the evolution of genomes across all life
domains.'Miniature Inverted-repeat Transposable-Elements'(MITEs) are non-autonomous …

High-throughput phenotype-to-genotype testing of meningococcal carriage and disease isolates detects genetic determinants of disease-relevant phenotypic traits

R Farzand, MW Kimani, E Mourkas, A Jama, JL Clark… - mBio, 2024 - journals.asm.org
Genome-wide association studies (GWAS) with binary or single phenotype data have
successfully identified disease-associated genotypes and determinants of antimicrobial …

Unveiling Neisseria gonorrhoeae Survival: Genetic Variability, Pathogenesis, and Antimicrobial Drug Resistance

BL Shaskolskiy, ID Kandinov, DA Gryadunov… - Molecular Biology, 2024 - Springer
Despite nearly a century of therapy for gonococcal infection with a variety of antimicrobials,
more than 80 million cases of the disease are reported annually worldwide. The gonorrhea …

Bridging Viruses and Prokaryotic Host through Miniature Inverted-repeat Transposable Elements (MITEs)

F Nadal-Molero, R Roselli, S Garcia-Juan… - bioRxiv, 2024 - biorxiv.org
Transposable elements (TEs) have a pivotal role in the evolution of genomes across all life
domains.“Miniature Inverted-repeat Transposable-Elements”(MITEs) are non-autonomous …

Diversity, Distribution, and Chromosomal Rearrangements of TRIP1 Repeat Sequences in Escherichia coli

Z Li, X Liu, N Ning, T Li, H Wang - Genes, 2024 - mdpi.com
The bacterial genome contains numerous repeated sequences that greatly affect its
genomic plasticity. The Escherichia coli K-12 genome contains three copies of the TRIP1 …

Gonococcal Genetic Island in the Global Neisseria gonorrhoeae Population: A Model of Genetic Diversity and Association with Resistance to Antimicrobials

D Kravtsov, D Gryadunov, B Shaskolskiy - Microorganisms, 2023 - mdpi.com
The aim of this work was to study the genetic diversity of the gonococcal genetic island (GGI)
responsible for the type IV secretion system (T4SS) and the association of a functionally …