Hyperhidrosis (HH) is a chronic disorder of excess sweat production that may have a
significant adverse effect on quality of life. A variety of treatment modalities currently exist to …

The clinical use of the anticholinergic glycopyrrolate dates back to the early 1960s when it
was first approved in the US Since then, oral and inhalation formulations have been …

BACKGROUND: Compensatory sweating is noted frequently after sympathectomy and may
be difficult to control in some patients. This prospective trial was projected to measure the …

Some individuals savor spicy foods, while others avoid them. Reasons underlying this range
of hedonic responses are unknown. The purpose of this study was to explore the basis for …

Background Effective topical treatment options for patients with primary axillary
hyperhidrosis (PAHH) are limited. A phase I trial showed promising results regarding the …

Background Idiopathic hyperhidrosis may be a disabling condition causing emotional stress
and negative impact on a patient's quality of life. Oral anticholinergics are one of the …

Primary focal hyperhidrosis is a disorder of idiopathic excessive sweating that typically
affects the axillae, palms, soles, and face. The disorder, which affects up to 2.8% of the US …

Primary focal hyperhidrosis is a disorder of excessive sweating that occurs in the axillae,
palms, soles, and craniofacial region in amounts greater than needed for thermal regulation …

Background Facial hyperhidrosis may negatively impact the quality of life. Although various
conservative modalities have been suggested, the condition is not often treated successfully …

Purpose: The objective of this study was to investigate the use of iontophoresis, soluble
microneedles and their combination for the transdermal delivery of glycopyrrolate. Methods …