Wound healing: a cellular perspective

M Rodrigues, N Kosaric, CA Bonham… - Physiological …, 2019 - journals.physiology.org
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Multi-functional wound dressings based on silicate bioactive materials

C Fan, Q Xu, R Hao, C Wang, Y Que, Y Chen, C Yang… - Biomaterials, 2022 - Elsevier
Most traditional wound dressings passively offer a protective barrier for the wounds, which
lacks the initiative in stimulating tissue regeneration. In addition, cutaneous wound healing …

[HTML][HTML] Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells

R Wei, Y Zhao, J Wang, X Yang, S Li… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Rationale: Colorectal cancer (CRC) is a common malignant tumor of the digestive system.
However, the efficacy of surgery and chemotherapy is limited. Ferroptosis is an iron-and …

Hypoxia-inducible factors and diabetes

JE Gunton - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Hypoxia can be defined as a relative deficiency in the amount of oxygen reaching the
tissues. Hypoxia-inducible factors (HIFs) are critical regulators of the mammalian response …

Bioactive injectable hydrogels containing desferrioxamine and bioglass for diabetic wound healing

L Kong, Z Wu, H Zhao, H Cui, J Shen… - … applied materials & …, 2018 - ACS Publications
Diabetic wound is hard to heal mainly because of the difficulty in vascularization in the
wound area. Accumulating results have shown that desferrioxamine (DFO) can promote …

The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability

M Jaśkiewicz, A Moszyńska, J Króliczewski… - Cellular & molecular …, 2022 - Springer
The hypoxia-inducible factors (HIF) are transcription factors that activate the adaptive
hypoxic response when oxygen levels are low. The HIF transcriptional program increases …

Molecular mechanisms of hair growth and regeneration: current understanding and novel paradigms

KS Houschyar, MR Borrelli, C Tapking, D Popp… - Dermatology, 2020 - karger.com
Hair is a defining feature of mammals and has critical functions, including protection,
production of sebum, apocrine sweat and pheromones, social and sexual interactions …

[HTML][HTML] Nanobiotechnology: applications in chronic wound healing

T Jiang, Q Li, J Qiu, J Chen, S Du, X Xu… - International journal …, 2022 - ncbi.nlm.nih.gov
Wounds occur when skin integrity is broken and the skin is damaged. With progressive
changes in the disease spectrum, the acute wounds caused by mechanical trauma have …

Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

A Kerstan, K Dieter, E Niebergall-Roth… - Stem Cell Research & …, 2022 - Springer
Background While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid
infections, amputations and life-threatening complications, DFUs often respond poorly to …

In what area of biology has a “new” type of cell death been discovered?

X Wang, J Lin, Z Li, M Wang - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Cell death is a fundamental physiological process that occurs in all organisms and is crucial
to each organism's evolution, ability to maintain a stable internal environment, and the …