Haemolytic uraemic syndrome

D Karpman, S Loos, R Tati… - Journal of internal …, 2017 - Wiley Online Library
Haemolytic uraemic syndrome (HUS) is defined by the simultaneous occurrence of
nonimmune haemolytic anaemia, thrombocytopenia and acute renal failure. This leads to …

Extrarenal manifestations of the hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli (STEC HUS)

M Khalid, S Andreoli - Pediatric Nephrology, 2019 - Springer
Hemolytic uremic syndrome is commonly caused by Shiga toxin-producing Escherichia coli
(STEC). Up to 15% of individuals with STEC-associated hemorrhagic diarrhea develop …

Roles of Shiga toxins in immunopathology

MS Lee, VL Tesh - Toxins, 2019 - mdpi.com
Shigella species and Shiga toxin-producing Escherichia coli (STEC) are agents of bloody
diarrhea that may progress to potentially lethal complications such as diarrhea-associated …

Eculizumab in typical hemolytic uremic syndrome (HUS) with neurological involvement

L Pape, H Hartmann, FC Bange, S Suerbaum… - Medicine, 2015 - journals.lww.com
Eculizumab in Typical Hemolytic Uremic Syndrome (HUS) With N... : Medicine Eculizumab in
Typical Hemolytic Uremic Syndrome (HUS) With Neurological Involvement : Medicine Log in …

Intermediate Follow-up of Pediatric Patients With Hemolytic Uremic Syndrome During the 2011 Outbreak Caused by E. coli O104:H4

S Loos, W Aulbert, B Hoppe… - Clinical Infectious …, 2017 - academic.oup.com
Abstract Background. In 2011 Escherichia coli O104: H4 caused an outbreak with> 800
cases of hemolytic uremic syndrome (HUS) in Germany, including 90 children. Data on the …

Pharmacological management of atypical hemolytic uremic syndrome in pediatric patients: current and future

E Gurevich, D Landau - Pediatric Drugs, 2023 - Springer
Atypical hemolytic uremic syndrome is a thrombotic microangiopathy characterized by
hemolysis, thrombocytopenia, and acute kidney injury, usually caused by alternative …

HUS and TTP: traversing the disease and the age spectrum

R Donadelli, A Sinha, A Bagga, M Noris… - Seminars in …, 2023 - Elsevier
Hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenia purpura (TTP) are rare
diseases sharing a common pathological feature, thrombotic microangiopathy (TMA). TMA is …

Shiga-Toxin E. coli Hemolytic Uremic Syndrome: Review of Management and Long-term Outcome

VJ Harkins, DA McAllister, BC Reynolds - Current Pediatrics Reports, 2020 - Springer
Abstract Purpose of Review We review the pathophysiology of Shiga-Toxin
Enteropathogenic–Hemolytic Uremic Syndrome (STEC-HUS), strategies to ameliorate or …

Hemolytic uremic syndrome associated with Escherichia coli O157:H7 infection in older adults: a case report and review of the literature

H Ko, H Maymani, C Rojas-Hernandez - Journal of Medical Case Reports, 2016 - Springer
Background Hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia
coli O157: H7 has been widely known as a common cause of acute renal failure in children …

Eculizumab in STEC-HUS: a paradigm shift in the management of pediatric patients with neurological involvement

DM Wildes, S Harvey, CS Costigan, C Sweeney… - Pediatric …, 2024 - Springer
Background Eculizumab for the treatment of atypical hemolytic uremic syndrome (HUS) is a
standard of care. Central nervous system (CNS) involvement in Shiga toxin–producing …