The future of precision medicine to predict outcomes and control tissue remodeling in inflammatory bowel disease

CA Lamb, A Saifuddin, N Powell, F Rieder - Gastroenterology, 2022 - Elsevier
Inflammatory bowel disease is characterized by significant interindividual heterogeneity.
With a wider selection of pharmacologic and nonpharmacologic interventions available and …

Psychiatric disorders in adult and paediatric patients with inflammatory bowel diseases–a systematic review and meta-analysis

L Arp, S Jansson, V Wewer… - Journal of Crohn's and …, 2022 - academic.oup.com
Background Inflammatory bowel diseases [IBD], which are associated with a high disease
burden, are also reported to be accompanied by a high prevalence of psychiatric disorders …

Longitudinal trajectories of anxiety, depression, and bipolar disorder in inflammatory bowel disease: a population-based cohort study

TH Bisgaard, G Poulsen, KH Allin, L Keefer… - …, 2023 - thelancet.com
Background Inflammatory bowel disease (IBD) is associated with psychiatric diseases, but it
is unclear to what degree patients with IBD are affected over their lifetime. We aimed to …

The alleviation of gut microbiota-induced depression and colitis in mice by anti-inflammatory probiotics NK151, NK173, and NK175

JW Yoo, YJ Shin, X Ma, YH Son, HM Jang, CK Lee… - Nutrients, 2022 - mdpi.com
Gut microbiota dysbiosis is strongly associated with psychiatric disorders and inflammatory
bowel disease (IBD). Herein, we examined whether the fecal microbiota of IBD patients with …

The association between inflammatory bowel disease and mental ill health: a retrospective cohort study using data from UK primary care

N Umar, D King, JS Chandan, N Bhala… - Alimentary …, 2022 - Wiley Online Library
Background Patients with active inflammatory bowel disease (IBD) and mental illnesses
experience worse IBD outcomes. Aim To describe the incidence of mental illnesses …

Inflammatory bowel diseases, interleukin-6 and interleukin-6 receptor subunit alpha in causal association with cerebral cortical structure: a Mendelian randomization …

C Liu, S Zhu, J Zhang, K Ren, K Li, J Yu - Frontiers in Immunology, 2023 - frontiersin.org
Background Neurological involvement and psychiatric manifestations have been
documented in clinical cases of inflammatory bowel disease (IBD); however, the presence of …

Constipation preceding depression: a population-based cohort study

Q Yun, S Wang, S Chen, H Luo, B Li, P Yip, X Yu… - …, 2024 - thelancet.com
Background Constipation is generally considered a common physical symptom of
depression or a side effect of antidepressant treatments. However, according to the gut-brain …

[HTML][HTML] Assessing the effect of interaction between gut microbiome and inflammatory bowel disease on the risks of depression

X Qin, C Pan, Q Cai, Y Zhao, D He, W Wei… - Brain, Behavior, & …, 2022 - Elsevier
Background Gut microbiome and inflammatory bowel disease (IBD) are implicated in the
development of depression, but the effect of their interactions on the risk of depression …

The burden of psychiatric manifestations in inflammatory bowel diseases: a systematic review with meta-analysis

S Massironi, A Pigoni, EAM Vegni… - Inflammatory bowel …, 2024 - academic.oup.com
Background Psychiatric disorders in patients with inflammatory bowel disease (IBD)
represent a significant but uncertain facet of the disease, with unsolved questions regarding …

DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota

LP Zhao, J Wu, W Quan, Y Zhou, H Hong… - The Journal of …, 2023 - Elsevier
Inflammatory bowel disease can cause pathological changes of certain organs, including
the gut and brain. As the major degradation route of tryptophan (Trp), Kynurenine (Kyn) …