Visible-light-mediated modification and manipulation of biomacromolecules
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …
have become crucial tools in chemical biology. They are extensively used not only to …
Human papillomavirus E6 and E7: the cervical cancer hallmarks and targets for therapy
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …
[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …
since work began exploring their supramolecular interactions with DNA. In recent years …
Combination of Ru (II) complexes and light: new frontiers in cancer therapy
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
Transition metal complexes as photosensitizers for integrated cancer theranostic applications
J Li, T Chen - Coordination Chemistry Reviews, 2020 - Elsevier
Light, oxygen and photosensitizers (PSs) are the three separate elements that have been
applied in combination in the phototherapy of cancers in the past decades. Currently …
applied in combination in the phototherapy of cancers in the past decades. Currently …
Human papillomavirus infection, cervical cancer and the less explored role of trace elements
AB Sravani, V Ghate, S Lewis - Biological Trace Element Research, 2023 - Springer
Cervical cancer is an aggressive type of cancer affecting women worldwide. Many affected
individuals rely on smear tests for the diagnosis, surgery, chemotherapy, or radiation for their …
individuals rely on smear tests for the diagnosis, surgery, chemotherapy, or radiation for their …
Targeting photoinduced DNA destruction by Ru (II) tetraazaphenanthrene in live cells by signal peptide
Exploiting NF-κB transcription factor peptide conjugation, a Ru (II)-bis-tap complex (tap= 1,
4, 5, 8-tetraazaphenanthrene) was targeted specifically to the nuclei of live HeLa and CHO …
4, 5, 8-tetraazaphenanthrene) was targeted specifically to the nuclei of live HeLa and CHO …
Photochemically active DNA-intercalating ruthenium and related complexes–insights by combining crystallography and transient spectroscopy
Recent research on the study of the interaction of ruthenium polypyridyl compounds and
defined sequence nucleic acids is reviewed. Particular emphasis is paid to complexes [Ru …
defined sequence nucleic acids is reviewed. Particular emphasis is paid to complexes [Ru …
[HTML][HTML] Relevance of infection with human papillomavirus: the role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins
B Ruttkay-Nedecky… - International …, 2013 - spandidos-publications.com
Human papillomaviruses (HPV) are small circular, double-stranded DNA viruses infecting
epithelial tissues. HPV types can be classified both as high-risk or low-risk. Of the more than …
epithelial tissues. HPV types can be classified both as high-risk or low-risk. Of the more than …