Head and neck paragangliomas: Recent advances in translational and clinical research and guidelines for patient care

S Richter, G Constantinescu, G Fancello… - Best Practice & …, 2024 - Elsevier
Head and neck paragangliomas (HNPGLs), rare neuroendocrine tumors that mainly arise
from parasympathetic ganglia along the cranial nerves, are challenging due to anatomic …

Paragangliomas of the Head and Neck: A Review of the Latest Diagnostic and Treatment Methods

DO Palade, R Hainarosie, A Zamfir, D Vrinceanu… - Medicina, 2024 - mdpi.com
Background and objectives: Paragangliomas of the head and neck are rare, slow-growing
neuroendocrine tumors, benign in their vast majority, but with a possibility of developing …

High incidence of occult familial SDHD cases amongst Czech patients with head and neck paragangliomas

A Guha, A Vicha, T Zelinka, M Kana, Z Musil… - Frontiers in …, 2023 - frontiersin.org
Introduction Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors,
which are mostly benign in nature. Amongst all genes, Succinate Dehydrogenase Subunit D …

Head and Neck Paraganglioma (HNPGL) Registry: A study protocol for prospective data collection in patients with Head and Neck Paragangliomas

CJM de Bresser, BPM van Nesselrooij… - Plos one, 2024 - journals.plos.org
Introduction There is a lack of comprehensive and uniform data on head and neck
paragangliomas (HNPGLs), and research is challenging due to its rarity and the involvement …

Somatostatin Receptor–Directed PET/CT Can Differentiate Between Different Subtypes of Head and Neck Paragangliomas

Y Zhi, E Gerhard-Hartmann, PE Hartrampf… - Clinical Nuclear …, 2023 - journals.lww.com
Somatostatin Receptor–Directed PET/CT Can Differentiate Betw... : Clinical Nuclear Medicine
Somatostatin Receptor–Directed PET/CT Can Differentiate Between Different Subtypes of …

Succinate dehydrogenase mutations in head and neck paragangliomas: A systematic review and meta‐analysis of individual patients' data

ES Koh, A Dabsha, M Rahouma, K Zappi… - Head & …, 2024 - Wiley Online Library
Background Head and neck paragangliomas (HNPs) have been associated with gene
mutations in the succinate dehydrogenase (SDH) complex, but the clinical significance …

Endovascular embolization as a stand-alone treatment of head and neck paragangliomas with long-term tumor control

S Michel, R Ludovichetti, G Bertalan… - American Journal …, 2024 - Am Soc Neuroradiology
ABSTRACT BACKGROUND AND PURPOSE: The impact of therapeutic embolization as a
stand-alone treatment of head and neck paragangliomas considered surgically high-risk …

[HTML][HTML] Single-cell RNA-Seq reveals the heterogeneity of fibroblasts within the tympanojugular paraganglioma microenvironment

S Wang, B Zhang, Z Lou, Y Hu, J Wang, J Wang… - Heliyon, 2024 - cell.com
Tympanojugular paragangliomas (TJP) originate from the parasympathetic ganglia in the
lateral base of the skull. Although the cellular composition and oncogenic mechanisms of …

Ultrastructural features of tumor‐associated mast cells in parasympathetic paragangliomas (chemodectomas) of the neck

I Chekmaryova, D Kalinin, A Kostin… - Microscopy …, 2024 - Wiley Online Library
The mechanisms of the pathogenesis of neck paraganglioma (PGL) and the possible role of
mast cells (MCs) in its development and metastasis are still poorly understood. We analyzed …

Head and Neck Paragangliomas: Overview of Institutional Experience

SN Vimawala, AZ Graboyes, B Bennett, M Bonanni… - Cancers, 2024 - mdpi.com
Simple Summary Head and neck paragangliomas (HNPGLs) are rare and have high rates of
genetic mutations. SDHx mutations currently account for the vast majority of mutations …