The inflamed brain in schizophrenia: the convergence of genetic and environmental risk factors that lead to uncontrolled neuroinflammation

AL Comer, M Carrier, MÈ Tremblay… - Frontiers in cellular …, 2020 - frontiersin.org
Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

Childhood trauma in schizophrenia: current findings and research perspectives

D Popovic, A Schmitt, L Kaurani, F Senner… - Frontiers in …, 2019 - frontiersin.org
Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms
throughout adult life in most of the affected patients. This unfavorable course is associated …

Child maltreatment in Germany: prevalence rates in the general population

A Witt, RC Brown, PL Plener, E Brähler… - Child and adolescent …, 2017 - Springer
Background Child maltreatment and its consequences are considered a major public health
problem. So far, there is only one study from Germany reporting prevalence rates on …

Examining associations, moderators and mediators between childhood maltreatment, social functioning, and social cognition in psychotic disorders: a systematic …

NE Fares-Otero, L Alameda, MC Pfaltz… - Psychological …, 2023 - cambridge.org
Childhood maltreatment (CM) has been related to social functioning and social cognition
impairment in people with psychotic disorders (PD); however, evidence across different CM …

Early life experiences and social cognition in major psychiatric disorders: A systematic review

KI Rokita, MR Dauvermann, G Donohoe - European psychiatry, 2018 - cambridge.org
Objective: To present a systematic review of the literature on the associations between early
social environment, early life adversity, and social cognition in major psychiatric disorders …

[HTML][HTML] The neural, stress hormone and inflammatory correlates of childhood deprivation and threat in psychosis: A systematic review

M Thomas, D Rakesh, S Whittle, M Sheridan… - …, 2023 - Elsevier
Childhood adversity increases the risk of developing psychosis, but the biological
mechanisms involved are unknown. Disaggregating early adverse experiences into core …

[HTML][HTML] The role of childhood trauma in cognitive performance in schizophrenia and bipolar disorder–A systematic review

MR Dauvermann, G Donohoe - Schizophrenia Research: Cognition, 2019 - Elsevier
Childhood trauma (CT) has repeatedly been associated with cognitive deficits in patients
with psychosis but many inconsistencies have been reported so that the nature of the …

Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants

KI Rokita, L Holleran, MR Dauvermann… - Social cognitive and …, 2020 - academic.oup.com
Childhood trauma, and in particular physical neglect, has been repeatedly associated with
lower performance on measures of social cognition (eg emotion recognition tasks) in both …

Mediating role of aberrant salience and self-disturbances for the relationship between childhood trauma and psychotic-like experiences in the general population

Ł Gawęda, AS Göritz, S Moritz - Schizophrenia research, 2019 - Elsevier
Introduction The relationship between childhood trauma and the risk of psychosis is well
established. However, the mechanisms of the relationship are still unknown. We …

Changes in default-mode network associated with childhood trauma in schizophrenia

MR Dauvermann, D Mothersill, KI Rokita… - Schizophrenia …, 2021 - academic.oup.com
Background There is considerable evidence of dysconnectivity within the default-mode
network (DMN) in schizophrenia, as measured during resting-state functional MRI (rs-fMRI) …