Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …

The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Rationale: Previous studies on the relationship between diabetes and arterial stiffness were
mostly cross-sectional. A few longitudinal studies focused on one single direction. Whether …

Importance Elevated systolic blood (SBP) pressure is a leading global health risk.
Quantifying the levels of SBP is important to guide prevention policies and interventions …

Excess reactive oxygen species production by mitochondria is a key mechanism of age-
related vascular dysfunction. Our laboratory has shown that supplementation with the …

An individual participant data meta-analysis was conducted in the data of 14 673 Japanese
participants without a history of cardiovascular disease (CVD) to examine the association of …

Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Cardiovascular diseases (CVD) account annually for almost one third of all deaths
worldwide. Among the CVD, systemic arterial hypertension (SAH) is related to more than …

Executive summary Elevated blood pressure is the strongest modifiable risk factor for
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …

Hypertension is both a cause and a consequence of central artery stiffening, which in turn is
an initiator and indicator of myriad disease conditions and thus all-cause mortality. Such …