[HTML][HTML] A critical review of the impact of candidate copy number variants on autism spectrum disorder
SS Abedini, S Akhavantabasi, Y Liang, J Heng… - … Research-Reviews in …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder (NDD)
influenced by genetic, epigenetic, and environmental factors. Recent advancements in …
influenced by genetic, epigenetic, and environmental factors. Recent advancements in …
[HTML][HTML] SOX7: novel autistic gene identified by analysis of multi-omics data
Background: Genome-wide association studies and next generation sequencing data
analyses based on DNA information have identified thousands of mutations associated with …
analyses based on DNA information have identified thousands of mutations associated with …
Spatial expression of the nonsense-mediated mRNA decay factors UPF3A and UPF3B among mouse tissues
X Ma, Y Li, C Chen, Y Shen, H Wang, T Li - Journal of Zhejiang University …, 2023 - Springer
Nonsense-mediated mRNA decay (NMD) is a highly conserved post-transcriptional gene
regulatory mechanism in eukaryotes (Lykke-Andersen and Jensen, 2015; Kurosaki et al …
regulatory mechanism in eukaryotes (Lykke-Andersen and Jensen, 2015; Kurosaki et al …
Group theory of messenger RNA metabolism and disease
Our recent work has focused on the application of infinite group theory and related algebraic
geometric tools in the context of transcription factors and microRNAs. We were able to …
geometric tools in the context of transcription factors and microRNAs. We were able to …
Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype
AA Eshraghi, I Memis, F Wang, I White, E Furar, J Mittal… - PloS one, 2022 - journals.plos.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in communication, and social skills, as well as repetitive and/or restrictive interests and …
in communication, and social skills, as well as repetitive and/or restrictive interests and …
mRNA metabolism in health and disease
L Romão - Biomedicines, 2022 - mdpi.com
Eukaryotic gene expression involves several interlinked steps, in which messenger RNAs
(mRNAs), which code for proteins, are the key intermediates. In the cell nucleus, the …
(mRNAs), which code for proteins, are the key intermediates. In the cell nucleus, the …
Posttranscriptional Control of Brain Development
The neocortex is among the newest evolutionary additions to the human brain, consistent
with its function in higher‐level processes such as cognition. This structure develops through …
with its function in higher‐level processes such as cognition. This structure develops through …
Direct and indirect effects of spliceosome disruption compromise gene regulation by Nonsense-Mediated mRNA Decay
CM Embree, A Stephanou, G Singh - bioRxiv, 2024 - biorxiv.org
Pre-mRNA splicing, carried out in the nucleus by a large ribonucleoprotein machine known
as the spliceosome, is functionally and physically coupled to the mRNA surveillance …
as the spliceosome, is functionally and physically coupled to the mRNA surveillance …
Screening and Bioinformatics Analysis of Differential Genes in Autism Spectrum Disorder Based on GEO Database
J Zhu, H Meng, Y Li - Advances in Biomedical and Bioinformatics …, 2023 - ebooks.iospress.nl
Objective: The prevalence of autism spectrum disorder (ASD) in children has been
increasing year by year, which has seriously affected the quality of life of children. There are …
increasing year by year, which has seriously affected the quality of life of children. There are …