Epithelial tissue responds rapidly to environmental triggers and is constantly renewed. This
tissue is also highly accessible for therapeutic targeting. This review highlights the role of …

These guidelines for the management of congenital ichthyoses have been developed by a
multidisciplinary group of European experts following a systematic review of the current …

Genetic skin diseases, or genodermatoses, often have extracutaneous manifestations.
Ocular manifestations in particular can have significant clinical implications, like blindness …

Purpose: To report our surgical experience with ocular surface stem cell transplantation
(OSST) for limbal stem cell deficiency (LSCD) in the setting of keratitis–ichthyosis–deafness …

Cell-to-cell communication triggered by connexin channels plays a central role in
maintaining epidermal homeostasis. Here, we discuss the role of the beta connexin …

Keratitis‐ichthyosis‐deafness syndrome is a rare genetic disease presenting with
cutaneous, ocular, and otic defects. This comprehensive review provides insight into the …

Congenital ichthyoses (CI) are rare genetic skin keratinisation diseases characterised by
generalised scaling and a variable degree of erythema and hyperkeratosis. Ocular …

Mutations in Connexin26 (C x26) give rise to a spectrum of dominantly inherited
hyperproliferating skin disorders, the severest being keratitis–ichthyosis–deafness (KID) …

We report the first case of Boston Keratoprosthesis (KPro) implantation in a 7-year-old girl
with keratitis-ichthyosiform-deafness syndrome and persistent, highly vascular corneal …

Plasma membrane-associated channels known as gap junctions, along with their protein
building blocks—connexins—have an important functional role in a range of immunological …