PAX6: 25th anniversary and more to learn

A Cvekl, P Callaerts - Experimental eye research, 2017 - Elsevier
The DNA-binding transcription factor PAX6 was cloned 25 years ago by multiple teams
pursuing identification of human and mouse eye disease causing genes, cloning vertebrate …

Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease

B Thompson, EA Davidson, W Liu, DW Nebert… - Human genetics, 2021 - Springer
Paired-box (PAX) genes encode a family of highly conserved transcription factors found in
vertebrates and invertebrates. PAX proteins are defined by the presence of a paired domain …

Lampreys, the jawless vertebrates, contain three Pax6 genes with distinct expression in eye, brain and pancreas

V Ravi, S Bhatia, P Shingate, BH Tay, B Venkatesh… - Scientific reports, 2019 - nature.com
The transcription factor Pax6 is crucial for the development of the central nervous system,
eye, olfactory system and pancreas, and is implicated in human disease. While a single …

PAX2 and CAKUT phenotypes: report on two New variants and a review of mutations from the Leiden Open Variation Database

S Negrisolo, E Benetti - International Journal of Molecular Sciences, 2023 - mdpi.com
PAX2 is a transcription factor expressed during embryogenesis in the eye, ear, CNS, and
genitourinary tract, and is one of the major regulators of kidney development. Mutations in …

Genetic analysis of medaka fish illuminates conserved and divergent roles of Pax6 in vertebrate eye development

S Mikula Mrstakova, Z Kozmik - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Landmark discovery of eye defects caused by Pax6 gene mutations in humans, rodents, and
even fruit flies combined with Pax6 gene expression studies in various phyla, led to the …

The Pax gene family: Highlights from cephalopods

S Navet, A Buresi, S Baratte, A Andouche… - PLoS …, 2017 - journals.plos.org
Pax genes play important roles in Metazoan development. Their evolution has been
extensively studied but Lophotrochozoa are usually omitted. We addressed the question of …

PAX2 expression is correlated with better survival in tamoxifen-treated breast carcinoma patients

R Jahangiri, F Mosaffa, M Gharib, ANE Razavi… - Tissue and Cell, 2018 - Elsevier
Abstract PAX2 (paired box gene 2) is a transcription factor, which is involved in both cell
proliferation and carcinogenesis. This study aimed to investigate PAX2 expression in …

Pax2 is essential for proliferation and osteogenic differentiation of mouse mesenchymal stem cells via Runx2

M Lu, S Guo, F Hong, Y Zhang, L Yuan, C Ma… - Experimental Cell …, 2018 - Elsevier
Mesenchymal stem cells (MSCs) have been widely studied in the field of regenerative
medicine with the potential to solve osteoporosis. Paired box 2 (Pax2), as a transcription …

配对盒基因8 和配对盒基因2 蛋白在上皮及肿瘤组织中的表达差异.

宋艳, 黄璇, 沈贵华, 刘秀云… - Chinese Journal of …, 2017 - search.ebscohost.com
配对盒基因8和配对盒基因2蛋白在上皮及肿瘤组织中的表达差异 Page 1 ·临床研究· 配对盒基因
8和配对盒基因2蛋白在上皮 及肿瘤组织中的表达差异 宋艳黄璇沈贵华刘秀云张询 100021 国家 …

Polymorphism in lncRNA AC016683. 6 and its interaction with smoking exposure on the susceptibility of lung cancer

J Li, H Li, X Lv, Z Yang, M Gao, Y Bi, Z Zhang… - Cancer Cell …, 2018 - Springer
Abstract Background Long non-coding RNAs play pivotal roles in the carcinogenesis of
multiple types of cancers. This study is firstly to evaluate influence of rs4848320 and …