Although surgery was the mainstay of treatment for valvular heart disease, transcatheter valve therapies have grown exponentially over the past decade. Two types of artificial heart …
IH Jaffer, JC Fredenburgh, J Hirsh… - Journal of Thrombosis …, 2015 - Wiley Online Library
Blood‐contacting medical devices, such as vascular grafts, stents, heart valves, and catheters, are often used to treat cardiovascular diseases. Thrombus formation is a common …
AH Schmaier - Journal of Thrombosis and Haemostasis, 2016 - Elsevier
The contact activation system (CAS) and kallikrein/kinin system (KKS) are older recognized biochemical pathways that include several proteins that skirt the fringes of the blood …
IH Jaffer, JI Weitz - Acta biomaterialia, 2019 - Elsevier
Blood-contacting medical devices are an integral part of modern medicine. Such devices may be used for only a few hours or may be implanted for life. Despite advances in …
AJ Doyle, BJ Hunt - Frontiers in medicine, 2018 - frontiersin.org
Extracorporeal membrane oxygenators are used in critical care for the management of severe respiratory and cardiac failure. Activation of the coagulation system is initiated by the …
X Liu, L Yuan, D Li, Z Tang, Y Wang, G Chen… - Journal of Materials …, 2014 - pubs.rsc.org
Devices that function in contact with blood are ubiquitous in clinical medicine and biotechnology. These devices include vascular grafts, coronary stents, heart valves …
Device-associated clot formation and poor tissue integration are ongoing problems with permanent and temporary implantable medical devices. These complications lead to …
NC Chan, JI Weitz - Circulation research, 2019 - Am Heart Assoc
Recent advances in our understanding of the contribution of thrombin generation to arterial thrombosis and the role of platelets in venous thrombosis have prompted new treatment …
Lubricant-infused omniphobic surfaces have exhibited outstanding effectiveness in inhibiting nonspecific adhesion and attenuating superimposed clot formation compared with …