Optimizing CAR-T treatment: A T2EVOLVE guide to raw and starting material selection

S Navarro, C Moukheiber, SI Sancho, MR Guillén… - Molecular Therapy, 2024 - cell.com
Chimeric antigen receptor (CAR)-T cell products, classified as Advanced Therapy Medicinal
Products (ATMPs), have shown promising outcomes in cancer immunotherapy. The quality …

In Vitro-Transcribed mRNAs as a New Generation of Therapeutics in the Dawn of Twenty-First Century: Exploitation of Peptides as Carriers for Their Intracellular …

AN Miliotou, IS Pappas, IS Vizirianakis… - Messenger RNA …, 2022 - Springer
In vitro-transcribed mRNAs (IVT-mRNAs) are easily and rapidly designed in vitro
synthesized RNA molecules. After their intracellular delivery through an efficient delivery …