Minimal residual disease detection in acute lymphoblastic leukemia

A Kruse, N Abdel-Azim, HN Kim, Y Ruan… - International journal of …, 2020 - mdpi.com
Minimal residual disease (MRD) refers to a chemotherapy/radiotherapy-surviving leukemia
cell population that gives rise to relapse of the disease. The detection of MRD is critical for …

Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities

B Burkhardt, ML Hermiston - British Journal of Haematology, 2019 - Wiley Online Library
Lymphoblastic lymphoma (LBL) is the second most common type of Non‐Hodgkin
Lymphoma (NHL) in childhood and adolescence, accounting for 25–35% of all cases. The …

ANPELA: Significantly Enhanced Quantification Tool for Cytometry‐Based Single‐Cell Proteomics

Y Zhang, H Sun, X Lian, J Tang, F Zhu - Advanced science, 2023 - Wiley Online Library
ANPELA is widely used for quantifying traditional bulk proteomic data. Recently, there is a
clear shift from bulk proteomics to the single‐cell ones (SCP), for which powerful cytometry …

CD123 expression levels in 846 acute leukemia patients based on standardized immunophenotyping

AE Bras, V de Haas, A van Stigt… - Cytometry Part B …, 2019 - Wiley Online Library
Background While it is known that CD123 is normally strongly expressed on plasmacytoid
dendritic cells and completely absent on nucleated red blood cells, detailed information …

Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

J Stutterheim, IM van der Sluis, P de Lorenzo… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Infant acute lymphoblastic leukemia (ALL) is characterized by a high incidence of
KMT2A gene rearrangements and poor outcome. We evaluated the value of minimal …

Early T-cell precursor acute lymphoblastic leukemia: diagnosis, updates in molecular pathogenesis, management, and novel therapies

C Sin, PM Man - Frontiers in oncology, 2021 - frontiersin.org
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a distinct subtype of T
lymphoblastic leukemia (T-ALL) identified in 2009, due to its unique immunophenotypic and …

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

O Hrusak, V De Haas, J Stancikova… - Blood, The Journal …, 2018 - ashpublications.org
Despite attempts to improve the definitions of ambiguous lineage leukemia (ALAL) during
the last 2 decades, general therapy recommendations are missing. Herein, we report a large …

Mechanisms of immune evasion in acute lymphoblastic leukemia

A Pastorczak, K Domka, K Fidyt, M Poprzeczko… - Cancers, 2021 - mdpi.com
Simple Summary Studies conducted in a recent decade revealed that acute lymphoblastic
leukemia cells exploit various mechanisms to avoid immune recognition and destruction by …

[HTML][HTML] DUX4r, ZNF384r and PAX5-P80R mutated B-cell precursor acute lymphoblastic leukemia frequently undergo monocytic switch

M Novakova, M Zaliova, K Fiser, B Vakrmanova… - …, 2021 - ncbi.nlm.nih.gov
Recently, we described B-cell precursor acute lymphoblastic leukemia (BCP-ALL) subtype
with an early switch to the monocytic lineage and the loss of the B-cell immunophenotype …

[HTML][HTML] Diagnosis and management of lymphoblastic lymphoma in children, adolescents and young adults

WC Temple, S Mueller, ML Hermiston… - Best Practice & Research …, 2023 - Elsevier
Lymphoblastic lymphoma (LBL) is the second most common type of non-Hodgkin
Lymphoma (NHL) in children, adolescents, and young adults (CAYA), accounting for 25 …