Biomarkers of stroke recovery: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable

LA Boyd, KS Hayward, NS Ward… - … Journal of Stroke, 2017 - journals.sagepub.com
The most difficult clinical questions in stroke rehabilitation are “What is this patient's potential
for recovery?” and “What is the best rehabilitation strategy for this person, given her/his …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association

RL Sacco, SE Kasner, JP Broderick, LR Caplan… - Stroke, 2013 - Am Heart Assoc
Despite the global impact and advances in understanding the pathophysiology of
cerebrovascular diseases, the term “stroke” is not consistently defined in clinical practice, in …

[HTML][HTML] Post-stroke cognitive impairment: epidemiology, mechanisms and management

JH Sun, L Tan, JT Yu - Annals of translational medicine, 2014 - ncbi.nlm.nih.gov
Post-stroke cognitive impairment occurs frequently in the patients with stroke. The
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …

Cerebral microbleeds: imaging and clinical significance

S Haller, MW Vernooij, JPA Kuijer, EM Larsson… - Radiology, 2018 - pubs.rsna.org
Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic
resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility …

Association of cerebral microbleeds with cognitive decline and dementia

S Akoudad, FJ Wolters, A Viswanathan… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral microbleeds are hypothesized downstream markers of brain damage
caused by vascular and amyloid pathologic mechanisms. To date, whether their presence is …

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup

RA Sperling, CR Jack Jr, SE Black, MP Frosch… - Alzheimer's & …, 2011 - Elsevier
Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with
multiple therapeutic avenues to lower amyloid-β burden in Alzheimer's disease (AD). In …

Cerebral microbleeds: a guide to detection and interpretation

SM Greenberg, MW Vernooij, C Cordonnier… - The Lancet …, 2009 - thelancet.com
Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in
individuals with cerebrovascular disease and dementia, and in normal ageing. There has …

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

AA Gouw, A Seewann, WM Van Der Flier… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background White matter hyperintensities (WMH), lacunes and microbleeds are regarded as
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …

The microbleed anatomical rating scale (MARS) reliability of a tool to map brain microbleeds

SM Gregoire, UJ Chaudhary, MM Brown, TA Yousry… - Neurology, 2009 - AAN Enterprises
Objective: Brain microbleeds on gradient-recalled echo (GRE) T2*-weighted MRI may be a
useful biomarker for bleeding-prone small vessel diseases, with potential relevance for …