Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …

Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

Innate immune signaling is essential for clearing pathogens and damaged cells and must be
tightly regulated to avoid excessive inflammation or autoimmunity. Here, we found that the …

Transposable elements (TEs) are abundant in the genomes of various eukaryote organisms.
Increasing evidence suggests that TEs can play crucial regulatory roles—usually by creating …

Retrotransposons are self-replicating genomic elements that move from one genomic
location to another using a “copy-and-paste” method involving RNA intermediaries. One …

Retrotransposons are transposable elements that are transposed via transcription and
reverse transcription. Their copies have accumulated in the genome of mammals, occupying …

Abstract Speckled Protein 140 (SP140) is a chromatin reader with critical roles regulating
immune cell transcriptional programs, and SP140 splice variants are associated with …

Transposable elements (TEs) are mobile genetic elements that constitute on average 45%
of mammalian genomes. Their presence and activity in genomes represent a major source …

The release and subsequent detection of nucleic acids into the cytoplasm constitute a
hallmark of the radiation-induced DNA damage response. However, different radiation …

Transposable elements (TEs) are key contributors to genetic novelty. Despite increasing
evidence of their importance, their roles in shaping the regulatory landscape of diverse …