Life after perinatal stroke

A Kirton, G Deveber - Stroke, 2013 - Am Heart Assoc
3266 Stroke November 2013 brain injury including stroke introduces multiple, often
competing factors in brain maturation and development that will ultimately determine …

Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management

RJ Felling, LR Sun, EC Maxwell, N Goldenberg… - Blood Cells, Molecules …, 2017 - Elsevier
Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic
morbidity in neonates and children, with consequences including hemiparesis, intellectual …

Antithrombotic therapy in neonates and children: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians Evidence-Based Clinical …

P Monagle, AKC Chan, NA Goldenberg, RN Ichord… - Chest, 2012 - Elsevier
Background Neonates and children differ from adults in physiology, pharmacologic
responses to drugs, epidemiology, and long-term consequences of thrombosis. This …

Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study

A Kirton, J Armstrong-Wells, T Chang, G Deveber… - …, 2011 - publications.aap.org
BACKGROUND: Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of
perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly …

Clinical characteristics, risk factors, and outcomes associated with neonatal hemorrhagic stroke: a population-based case-control study

L Cole, D Dewey, N Letourneau, BJ Kaplan… - JAMA …, 2017 - jamanetwork.com
Importance Hemorrhage into the brain of term newborns often results in major injury and
lifelong disability. The clinical epidemiology of neonatal hemorrhagic stroke (NHS) remains …

Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke

CTJ Van Velthoven, RA Sheldon, A Kavelaars… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Brain injury caused by stroke is a frequent cause of perinatal
morbidity and mortality with limited therapeutic options. Mesenchymal stem cells (MSC) …

Perinatal stroke: mapping and modulating developmental plasticity

A Kirton, MJ Metzler, BT Craig, A Hilderley… - Nature Reviews …, 2021 - nature.com
Most cases of hemiparetic cerebral palsy are caused by perinatal stroke, resulting in lifelong
disability for millions of people. However, our understanding of how the motor system …

Mesenchymal stem cell‐based treatments for stroke, neural trauma, and heat stroke

YCY Hsuan, CH Lin, CP Chang, MT Lin - Brain and behavior, 2016 - Wiley Online Library
Background Mesenchymal stem cell (MSC) transplantation has been reported to improve
neurological function following neural injury. Many physiological and molecular …

Pathophysiology of cerebral palsy

S Marret, C Vanhulle, A Laquerriere - Handbook of clinical neurology, 2013 - Elsevier
Cerebral palsy (CP), defined as a group of nonprogressive disorders of movement and
posture, is the most common cause of severe neurodisability in children. Understanding its …

Cerebral palsy: Aetiology, pathophysiology and therapeutic interventions

J Upadhyay, N Tiwari, MN Ansari - Clinical and Experimental …, 2020 - Wiley Online Library
Cerebral palsy (CP) is the most common non‐progressive neurodevelopmental disorder in
which the impairment of motor and posture functions occurs. This condition may be present …